Size Matters: The Functional Role of the CEACAM1 Isoform Signature and Its Impact for NK Cell-Mediated Killing in Melanoma

by Iris Helfrich, Bernhard B. Singer
Published 2019-03-01

Tension in Cancer

by Stefanie Löffek, Claus-Werner Franzke, Iris Helfrich
Published 2016-11-01

Ex Vivo Exposure of Human Melanoma Tissue to Cold Physical Plasma Elicits Apoptosis and Modulates Inflammation

by Sander Bekeschus, Juliane Moritz, Iris Helfrich, Lars Boeckmann, Klaus-Dieter Weltmann, Steffen Emmert, Hans-Robert Metelmann, Ingo Stoffels, Thomas von Woedtke
Published 2020-03-01

Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis

by Alexander Carpinteiro, Nadine Beckmann, Aaron Seitz, Gabriele Hessler, Barbara Wilker, Matthias Soddemann, Iris Helfrich, Bärbel Edelmann, Erich Gulbins, Katrin Anne Becker
Published 2016-01-01

Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth

by Johanna C. Klein, Katrin Moses, Gennadiy Zelinskyy, Simon Sody, Jan Buer, Stephan Lang, Iris Helfrich, Ulf Dittmer, Carsten J. Kirschning, Sven Brandau
Published 2017-03-01

Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

by Miriam Schöpel, Oleksandr Shkura, Jana Seidel, Klaus Kock, Xueyin Zhong, Stefanie Löffek, Iris Helfrich, Hagen S. Bachmann, Jürgen Scherkenbeck, Christian Herrmann, Raphael Stoll
Published 2018-04-01

Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain

by Dayana Herrera-Rios, Dayana Herrera-Rios, Sadaf S. Mughal, Sarah Teuber-Hanselmann, Daniela Pierscianek, Daniela Pierscianek, Antje Sucker, Antje Sucker, Philipp Jansen, Philipp Jansen, Tobias Schimming, Tobias Schimming, Joachim Klode, Joachim Klode, Julia Reifenberger, Jörg Felsberg, Kathy Keyvani, Benedikt Brors, Ulrich Sure, Ulrich Sure, Guido Reifenberger, Guido Reifenberger, Dirk Schadendorf, Dirk Schadendorf, Iris Helfrich, Iris Helfrich
Published 2020-02-01

Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia

by Ralph Klose, Ewelina Krzywinska, Magali Castells, Dagmar Gotthardt, Eva Maria Putz, Chahrazade Kantari-Mimoun, Naima Chikdene, Anna-Katharina Meinecke, Katrin Schrödter, Iris Helfrich, Joachim Fandrey, Veronika Sexl, Christian Stockmann
Published 2016-08-01

Integrative Genomic Analyses of Patient-Matched Intracranial and Extracranial Metastases Reveal a Novel Brain-Specific Landscape of Genetic Variants in Driver Genes of Malignant Me...

by Renáta Váraljai, Susanne Horn, Antje Sucker, Daniela Piercianek, Verena Schmitt, Alexander Carpinteiro, Katrin Anne Becker, Julia Reifenberger, Alexander Roesch, Joerg Felsberg, Guido Reifenberger, Ulrich Sure, Dirk Schadendorf, Iris Helfrich
Published 2021-02-01

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

by Halime Kalkavan, Piyush Sharma, Stefan Kasper, Iris Helfrich, Aleksandra A. Pandyra, Asmae Gassa, Isabel Virchow, Lukas Flatz, Tim Brandenburg, Sukumar Namineni, Mathias Heikenwalder, Bastian Höchst, Percy A. Knolle, Guido Wollmann, Dorothee von Laer, Ingo Drexler, Jessica Rathbun, Paula M. Cannon, Stefanie Scheu, Jens Bauer, Jagat Chauhan, Dieter Häussinger, Gerald Willimsky, Max Löhning, Dirk Schadendorf, Sven Brandau, Martin Schuler, Philipp A. Lang, Karl S. Lang
Published 2017-03-01