Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

by Chao Liu, Hyowon Choi, Zariel I. Johnson, Jiwei Tian, Irving M. Shapiro, Makarand V. Risbud
Published 2017-07-01

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

by Christophe Merceron, Laura Mangiavini, Alexander Robling, Tremika LeShan Wilson, Amato J Giaccia, Irving M Shapiro, Ernestina Schipani, Makarand V Risbud
Published 2014-01-01

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections.

by Jessica M Gilbertie, Lauren V Schnabel, Noreen J Hickok, Megan E Jacob, Brian P Conlon, Irving M Shapiro, Javad Parvizi, Thomas P Schaer
Published 2019-01-01

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

by Emanuel J. Novais, Victoria A. Tran, Shira N. Johnston, Kayla R. Darris, Alex J. Roupas, Garrett A. Sessions, Irving M. Shapiro, Brian O. Diekman, Makarand V. Risbud
Published 2021-09-01