A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters.

by Amin Mahpour, Benjamin S Scruggs, Dominic Smiraglia, Toru Ouchi, Irwin H Gelman
Published 2018-01-01

Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.

by Hyun-Kyung Ko, Li-wu Guo, Bing Su, Lingqiu Gao, Irwin H Gelman
Published 2014-01-01

A genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer.

by Bing Su, Lingqiu Gao, Catherine Baranowski, Bryan Gillard, Jianmin Wang, Ryan Ransom, Hyun-Kyung Ko, Irwin H Gelman
Published 2014-01-01

Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase SignalingSummary

by Jianliang Zhang, Irwin H. Gelman, Eriko Katsuta, Yuanzi Liang, Xue Wang, Jun Li, Jun Qu, Li Yan, Kazuaki Takabe, Steven N. Hochwald
Published 2019-01-01

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer

by Yinglong Zhang, He Shen, Henry G. Withers, Nuo Yang, Kayla E. Denson, Ashley L. Mussell, Alexander Truskinovsky, Qingyu Fan, Irwin H. Gelman, Costa Frangou, Jianmin Zhang
Published 2017-07-01

Retinoid-induced expression and activity of an immediate early tumor suppressor gene in vascular smooth muscle cells.

by Jeffrey W Streb, Xiaochun Long, Ting-Hein Lee, Qiang Sun, Chad M Kitchen, Mary A Georger, Orazio J Slivano, William S Blaner, Daniel W Carr, Irwin H Gelman, Joseph M Miano
Published 2011-04-01

AKAP12 Supports Blood-Brain Barrier Integrity against Ischemic Stroke

by Ji Hae Seo, Takakuni Maki, Nobukazu Miyamoto, Yoon Kyong Choi, Kelly K. Chung, Gen Hamanaka, Ji Hyun Park, Emiri T. Mandeville, Hajime Takase, Kazuhide Hayakawa, Josephine Lok, Irwin H. Gelman, Kyu-Won Kim, Eng H. Lo, Ken Arai
Published 2020-11-01

AKAP12 mediates barrier functions of fibrotic scars during CNS repair.

by Jong-Ho Cha, Hee-Jun Wee, Ji Hae Seo, Bum Ju Ahn, Ji-Hyeon Park, Jun-Mo Yang, Sae-Won Lee, Eun Hee Kim, Ok-Hee Lee, Ji Hoe Heo, Hyo-Jong Lee, Irwin H Gelman, Ken Arai, Eng H Lo, Kyu-Won Kim
Published 2014-01-01