RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stages

by Arunasalam Naguleswaran, Nicholas Doiron, Isabel Roditi
Published 2018-04-01

A transient CRISPR/Cas9 expression system for genome editing in Trypanosoma brucei

by Sebastian Shaw, Sebastian Knüsel, Sarah Hoenner, Isabel Roditi
Published 2020-06-01

Bottlenecks and the maintenance of minor genotypes during the life cycle of Trypanosoma brucei.

by Michael Oberle, Oliver Balmer, Reto Brun, Isabel Roditi
Published 2010-07-01

Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel.

by Lucien Rufener, Pascal Mäser, Isabel Roditi, Ronald Kaminsky
Published 2009-04-01

Social motility of African trypanosomes is a property of a distinct life-cycle stage that occurs early in tsetse fly transmission.

by Simon Imhof, Sebastian Knüsel, Kapila Gunasekera, Xuan Lan Vu, Isabel Roditi
Published 2014-10-01

An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition.

by Shubha Bevkal, Arunasalam Naguleswaran, Ruth Rehmann, Marcel Kaiser, Manfred Heller, Isabel Roditi
Published 2021-01-01

PSSA-2, a membrane-spanning phosphoprotein of Trypanosoma brucei, is required for efficient maturation of infection.

by Cristina M Fragoso, Gabriela Schumann Burkard, Michael Oberle, Christina Kunz Renggli, Karen Hilzinger, Isabel Roditi
Published 2009-09-01

Spliced leader trapping reveals widespread alternative splicing patterns in the highly dynamic transcriptome of Trypanosoma brucei.

by Daniel Nilsson, Kapila Gunasekera, Jan Mani, Magne Osteras, Laurent Farinelli, Loic Baerlocher, Isabel Roditi, Torsten Ochsenreiter
Published 2010-08-01

Flagellar cAMP signaling controls trypanosome progression through host tissues

by Sebastian Shaw, Stephanie F. DeMarco, Ruth Rehmann, Tanja Wenzler, Francesca Florini, Isabel Roditi, Kent L. Hill
Published 2019-02-01

Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication? [version 1; referees: 2 approved]

by Simon Imhof, Cristina Fragoso, Andrew Hemphill, Conrad von Schubert, Dong Li, Wesley Legant, Eric Betzig, Isabel Roditi
Published 2016-04-01

Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery.

by Jan Mani, Andreas Güttinger, Bernd Schimanski, Manfred Heller, Alvaro Acosta-Serrano, Pascale Pescher, Gerald Späth, Isabel Roditi
Published 2011-01-01

Expression of procyclin mRNAs during cyclical transmission of Trypanosoma brucei.

by Simon Urwyler, Erik Vassella, Jan Van Den Abbeele, Christina Kunz Renggli, Pat Blundell, J David Barry, Isabel Roditi
Published 2005-11-01

Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse.

by Erik Vassella, Michael Oberle, Simon Urwyler, Christina Kunz Renggli, Erwin Studer, Andrew Hemphill, Cristina Fragoso, Peter Bütikofer, Reto Brun, Isabel Roditi
Published 2009-01-01

An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.

by Juan P de Macêdo, Gabriela Schumann Burkard, Moritz Niemann, Michael P Barrett, Henri Vial, Pascal Mäser, Isabel Roditi, André Schneider, Peter Bütikofer
Published 2015-05-01

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

by Fabian Hulpia, Dorien Mabille, Gustavo D. Campagnaro, Gabriela Schumann, Louis Maes, Isabel Roditi, Anders Hofer, Harry P. de Koning, Guy Caljon, Serge Van Calenbergh
Published 2019-12-01