Myeloid Lineage Ablation of <i>Phlpp1</i> Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice

by Ismael Y. Karkache, Jeyaram R. Damodaran, David H. H. Molstad, Kim C. Mansky, Elizabeth W. Bradley
Published 2021-09-01

Phlpp1 is induced by estrogen in osteoclasts and its loss in Ctsk-expressing cells does not protect against ovariectomy-induced bone loss.

by Marcelline K Hanson, Ismael Y Karkache, David H H Molstad, Andrew A Norton, Kim C Mansky, Elizabeth W Bradley
Published 2021-01-01