Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors

by Tomas Koblas, Ivan Leontovyc, Sarka Loukotova, Lucie Kosinova, Frantisek Saudek
Published 2016-01-01

Synthetic mRNA is a more reliable tool for the delivery of DNA-targeting proteins into the cell nucleus than fusion with a protein transduction domain.

by Ivan Leontovyc, David Habart, Sarka Loukotova, Lucie Kosinova, Jan Kriz, Frantisek Saudek, Tomas Koblas
Published 2017-01-01

Unstable Expression of Commonly Used Reference Genes in Rat Pancreatic Islets Early after Isolation Affects Results of Gene Expression Studies.

by Lucie Kosinová, Monika Cahová, Eva Fábryová, Irena Týcová, Tomáš Koblas, Ivan Leontovyč, František Saudek, Jan Kříž
Published 2016-01-01

Combining Donor Characteristics with Immunohistological Data Improves the Prediction of Islet Isolation Success

by Zuzana Berkova, Frantisek Saudek, Peter Girman, Klara Zacharovova, Jan Kriz, Eva Fabryova, Ivan Leontovyc, Tomas Koblas, Lucie Kosinova, Tomas Neskudla, Ema Vavrova, David Habart, Sarka Loukotova, Martina Zahradnicka, Kvetoslav Lipar, Ludek Voska, Jelena Skibova
Published 2016-01-01