Serial block face scanning electron microscopy reveals novel organizational details of the retinal pigment epithelium

by J Arjuna Ratnayaka, Eloise Keeling
Published 2022-01-01

Challenges in studying geographic atrophy (GA) age-related macular degeneration: the potential of a new mouse model with GA-like features

by J Arjuna Ratnayaka, Andrew J Lotery
Published 2020-01-01

Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

by Eloise Keeling, Andrew J. Lotery, David A. Tumbarello, J. Arjuna Ratnayaka
Published 2018-02-01

The complexities underlying age-related macular degeneration: could amyloid beta play an important role?

by Savannah A Lynn, Eloise Keeling, Rosie Munday, Gagandeep Gabha, Helen Griffiths, Andrew J Lotery, J Arjuna Ratnayaka
Published 2017-01-01

An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy

by Eloise Keeling, Annabelle J. Culling, David A. Johnston, David S. Chatelet, Anton Page, David A. Tumbarello, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2020-09-01

3D-Reconstructed Retinal Pigment Epithelial Cells Provide Insights into the Anatomy of the Outer Retina

by Eloise Keeling, David S. Chatelet, Nicole Y. T. Tan, Farihah Khan, Rhys Richards, Thibana Thisainathan, Patricia Goggin, Anton Page, David A. Tumbarello, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2020-11-01

A convenient protocol for establishing a human cell culture model of the outer retina. [version 1; referees: 2 approved]

by Savannah A. Lynn, Eloise Keeling, Jennifer M. Dewing, David A. Johnston, Anton Page, Angela J. Cree, David A. Tumbarello, Tracey A. Newman, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2018-07-01

Oligomeric Aβ_1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

by Savannah A. Lynn, David A. Johnston, Jenny A. Scott, Rosie Munday, Roshni S. Desai, Eloise Keeling, Ruaridh Weaterton, Alexander Simpson, Dillon Davis, Thomas Freeman, David S. Chatelet, Anton Page, Angela J. Cree, Helena Lee, Tracey A. Newman, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2021-02-01

A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping

by Luke O’Gorman, Chelsea S. Norman, Luke Michaels, Tutte Newall, Andrew H. Crosby, Christopher Mattocks, Angela J. Cree, Andrew J. Lotery, Emma L. Baple, J. Arjuna Ratnayaka, Diana Baralle, Helena Lee, Daniel Osborne, Fatima Shawkat, Jane Gibson, Sarah Ennis, Jay E. Self
Published 2019-09-01

Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B)

by Chelsea S. Norman, Luke O’Gorman, Jane Gibson, Reuben J. Pengelly, Diana Baralle, J. Arjuna Ratnayaka, Helen Griffiths, Matthew Rose-Zerilli, Megan Ranger, David Bunyan, Helena Lee, Rhiannon Page, Tutte Newall, Fatima Shawkat, Christopher Mattocks, Daniel Ward, Sarah Ennis, Jay E. Self
Published 2017-06-01