Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim.

by Kostas Paschos, Paul Smith, Emma Anderton, Jaap M Middeldorp, Robert E White, Martin J Allday
Published 2009-06-01

Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas

by Octavia Ramayanti, Mitch Brinkkemper, Sandra A. W. M. Verkuijlen, Leni Ritmaleni, Mei Lin Go, Jaap M. Middeldorp
Published 2018-03-01

The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells.

by Xiaochen Lin, Ming-Han Tsai, Anatoliy Shumilov, Remy Poirey, Helmut Bannert, Jaap M Middeldorp, Regina Feederle, Henri-Jacques Delecluse
Published 2015-12-01

Telomerase activity impacts on Epstein-Barr virus infection of AGS cells.

by Jürgen Rac, Florian Haas, Andrina Schumacher, Jaap M Middeldorp, Henri-Jacques Delecluse, Roberto F Speck, Michele Bernasconi, David Nadal
Published 2015-01-01

Epstein-Barr DNA in advanced pediatric nasopharyngeal cancer

by Marlinda Adham, Namira Kesuma Jelita, Djajadiman Gatot, Soehartati Argadikoesoema Gondhowiardjo, Lisnawati Rachmadi, Astrid E Greijer, I Bing Tan, Jaap M Middeldorp
Published 2021-09-01

High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7.

by Sirinart Aromseree, Jaap M Middeldorp, Chamsai Pientong, Monique van Eijndhoven, Octavia Ramayanti, Sinéad M Lougheed, D Michiel Pegtel, Renske D M Steenbergen, Tipaya Ekalaksananan
Published 2017-01-01

Seroprevalence of IgA anti Epstein-Barr virus is high among family members of nasopharyngeal cancer patients and individuals presenting with chronic complaints in head and neck are...

by Susanna Hilda Hutajulu, Jajah Fachiroh, Gabriella Argy, Sagung Rai Indrasari, Luh Putu Lusy Indrawati, Dewi Kartikawati Paramita, Theodola Baning Rahayu Jati, Jaap M Middeldorp
Published 2017-01-01

Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes

by Frederik J. Verweij, Cecilia de Heus, Stefanie Kroeze, Houjian Cai, Elliott Kieff, Sander R. Piersma, Connie R. Jimenez, Jaap M. Middeldorp, Dirk Michiel Pegtel
Published 2015-04-01

Development of a non-invasive method, multiplex methylation specific PCR (MMSP), for early diagnosis of nasopharyngeal carcinoma.

by Zhe Zhang, Di Sun, Susanna Hilda Hutajulu, Imran Nawaz, Do Nguyen Van, Guangwu Huang, Sofia M Haryana, Jaap M Middeldorp, Ingemar Ernberg, Li-Fu Hu
Published 2012-01-01

Current status of cancer care for young patients with nasopharyngeal carcinoma in Jakarta, Indonesia.

by Marlinda Adham, Sharon D Stoker, Maarten A Wildeman, Lisnawati Rachmadi, Soehartati Gondhowiardjo, Djumhana Atmakusumah, Djayadiman Gatot, Renske Fles, Astrid E Greijer, Bambang Hermani, Jaap M Middeldorp, I Bing Tan
Published 2014-01-01

Short-term effect of different teaching methods on nasopharyngeal carcinoma for general practitioners in Jakarta, Indonesia.

by Maarten A Wildeman, Renske Fles, Marlinda Adham, Ika D Mayangsari, Ilse Luirink, Mara Sandberg, Andrew D Vincent, Faiziah Fardizza, Zanil Musa, Armiyanto, Jaap M Middeldorp, Geerten Gerritsen, Ronny Suwanto, I Bing Tan
Published 2012-01-01

Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle.

by Nathan P Croft, Claire Shannon-Lowe, Andrew I Bell, Daniëlle Horst, Elisabeth Kremmer, Maaike E Ressing, Emmanuel J H J Wiertz, Jaap M Middeldorp, Martin Rowe, Alan B Rickinson, Andrew D Hislop
Published 2009-06-01

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

by Danijela Koppers-Lalic, Michael Hackenberg, Irene V. Bijnsdorp, Monique A.J. van Eijndhoven, Payman Sadek, Daud Sie, Nicoletta Zini, Jaap M. Middeldorp, Bauke Ylstra, Renee X. de Menezes, Thomas Würdinger, Gerrit A. Meijer, D. Michiel Pegtel
Published 2014-09-01

Primary treatment results of Nasopharyngeal Carcinoma (NPC) in Yogyakarta, Indonesia.

by Maarten A Wildeman, Renske Fles, Camelia Herdini, Rai S Indrasari, Andrew D Vincent, Maesadji Tjokronagoro, Sharon Stoker, Johan Kurnianda, Baris Karakullukcu, Kartika W Taroeno-Hariadi, Olga Hamming-Vrieze, Jaap M Middeldorp, Bambang Hariwiyanto, Sofia M Haryana, I Bing Tan
Published 2013-01-01