Increased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory response.

by Jacqueline Surls, Cristina Nazarov-Stoica, Margaret Kehl, Cara Olsen, Sofia Casares, Teodor-D Brumeanu
Published 2012-01-01

Double negative (CD3+ 4- 8-) TCR alphabeta splenic cells from young NOD mice provide long-lasting protection against type 1 diabetes.

by Beverly Duncan, Cristina Nazarov-Stoica, Jacqueline Surls, Margaret Kehl, Constantin Bona, Sofia Casares, Teodor-D Brumeanu
Published 2010-07-01

Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells.

by Rebecca Danner, Snehal N Chaudhari, John Rosenberger, Jacqueline Surls, Thomas L Richie, Teodor-Doru Brumeanu, Sofia Casares
Published 2011-01-01