Translating Developmental Principles to Generate Human Gastric Organoids

by Alexandra K. Eicher, H. Matthew Berns, James M. Wells
Published 2018-01-01

Case Report: Esophageal Bronchus in a Neonate, With Image, Histological, and Molecular Analysis

by Stephen L. Trisno, Nara S. Higano, Dan Kechele, Talia Nasr, Wendy Chung, Aaron M. Zorn, Aaron M. Zorn, Jason C. Woods, Jason C. Woods, James M. Wells, James M. Wells, James M. Wells, Paul S. Kingma, Paul S. Kingma
Published 2021-07-01

ST6GAL1 and α2-6 Sialylation Regulates IL-6 Expression and Secretion in Chronic Obstructive Pulmonary Disease

by Stefanie Krick, Stefanie Krick, E. Scott Helton, Molly Easter, Seth Bollenbecker, Rebecca Denson, Rennan Zaharias, Phillip Cochran, Shia Vang, Elex Harris, Elex Harris, James M. Wells, James M. Wells, James M. Wells, Jarrod W. Barnes, Jarrod W. Barnes
Published 2021-07-01

Evaluation of transplantation sites for human intestinal organoids.

by Akaljot Singh, Holly M Poling, Nambirajan Sundaram, Nicole Brown, James M Wells, Michael A Helmrath
Published 2020-01-01

Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium.

by Alexander W Lange, Angela R Keiser, James M Wells, Aaron M Zorn, Jeffrey A Whitsett
Published 2009-05-01

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.

by Diva Jonatan, Jason R Spence, Anna M Method, Matthew Kofron, Katie Sinagoga, Leena Haataja, Peter Arvan, Gail H Deutsch, James M Wells
Published 2014-01-01

Tissue Responses to Shiga Toxin in Human Intestinal OrganoidsSummary

by Suman Pradhan, Sayali S. Karve, Alison A. Weiss, Jennifer Hawkins, Holly M. Poling, Michael A. Helmrath, James M. Wells, Heather A. McCauley
Published 2020-01-01

Defining the molecular pathologies in cloaca malformation: similarities between mouse and human

by Laura A. Runck, Anna Method, Andrea Bischoff, Marc Levitt, Alberto Peña, Margaret H. Collins, Anita Gupta, Shiva Shanmukhappa, James M. Wells, Géraldine Guasch
Published 2014-04-01

Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids

by Ali Nowrouzi, Mathieu G. Sertorio, Mahdi Akbarpour, Maximillian Knoll, Damir Krunic, Matthew Kuhar, Christian Schwager, Stephan Brons, Jürgen Debus, Susanne I. Wells, James M. Wells, Amir Abdollahi
Published 2020-02-01

Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.

by Loryn Holokai, Jayati Chakrabarti, Taylor Broda, Julie Chang, Jennifer A Hawkins, Nambirajan Sundaram, Lydia E Wroblewski, Richard M Peek, Jiang Wang, Michael Helmrath, James M Wells, Yana Zavros
Published 2019-01-01

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification

by Scott A. Rankin, Lu Han, Kyle W. McCracken, Alan P. Kenny, Christopher T. Anglin, Emily A. Grigg, Calyn M. Crawford, James M. Wells, John M. Shannon, Aaron M. Zorn
Published 2016-06-01

Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage

by Timothy M. Chlon, Sonya Ruiz-Torres, Logan Maag, Christopher N. Mayhew, Kathryn A. Wikenheiser-Brokamp, Stella M. Davies, Parinda Mehta, Kasiani C. Myers, James M. Wells, Susanne I. Wells
Published 2016-01-01

Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.

by Yaron Suissa, Judith Magenheim, Miri Stolovich-Rain, Ayat Hija, Patrick Collombat, Ahmed Mansouri, Lori Sussel, Beatriz Sosa-Pineda, Kyle McCracken, James M Wells, R Scott Heller, Yuval Dor, Benjamin Glaser
Published 2013-01-01

Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport

by Heather A. McCauley, Andrea L. Matthis, Jacob R. Enriquez, Jonah T. Nichol, J. Guillermo Sanchez, William J. Stone, Nambirajan Sundaram, Michael A. Helmrath, Marshall H. Montrose, Eitaro Aihara, James M. Wells
Published 2020-09-01

Disruption of a Hedgehog-Foxf1-Rspo2 signaling axis leads to tracheomalacia and a loss of Sox9+ tracheal chondrocytes

by Talia Nasr, Andrea M. Holderbaum, Praneet Chaturvedi, Kunal Agarwal, Jessica L. Kinney, Keziah Daniels, Stephen L. Trisno, Vladimir Ustiyan, John M. Shannon, James M. Wells, Debora Sinner, Vladimir V. Kalinichenko, Aaron M. Zorn
Published 2021-02-01

In vitro generation of human pluripotent stem cell derived lung organoids

by Briana R Dye, David R Hill, Michael AH Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein, Eric S White, Gail H Deutsch, Jason R Spence
Published 2015-03-01

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis

by Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike, Talia Nasr, Kentaro Iwasawa, Kirsten Giesbrecht, Phillip C. Witcher, Alexandra Eicher, Lauren Haines, Yarim Lee, John M. Shannon, Mitsuru Morimoto, James M. Wells, Takanori Takebe, Aaron M. Zorn
Published 2020-08-01