p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice

by Darren J. Baker, Robbyn L. Weaver, Jan M. van Deursen
Published 2013-04-01

Reprogramming to pluripotency can conceal somatic cell chromosomal instability.

by Masakazu Hamada, Liviu A Malureanu, Tobias Wijshake, Wei Zhou, Jan M van Deursen
Published 2012-01-01

Cdc20 is critical for meiosis I and fertility of female mice.

by Fang Jin, Masakazu Hamada, Liviu Malureanu, Karthik B Jeganathan, Wei Zhou, Dean E Morbeck, Jan M van Deursen
Published 2010-09-01

BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer

by Robbyn L Weaver, Jazeel F Limzerwala, Ryan M Naylor, Karthik B Jeganathan, Darren J Baker, Jan M van Deursen
Published 2016-08-01

Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation.

by Tobias Wijshake, Liviu A Malureanu, Darren J Baker, Karthik B Jeganathan, Bart van de Sluis, Jan M van Deursen
Published 2012-01-01

Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I

by Warif El Yakoubi, Eulalie Buffin, Damien Cladière, Yulia Gryaznova, Inés Berenguer, Sandra A. Touati, Rocío Gómez, José A. Suja, Jan M. van Deursen, Katja Wassmann
Published 2017-09-01

ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

by Somaira Nowsheen, Khaled Aziz, Kuntian Luo, Min Deng, Bo Qin, Jian Yuan, Karthik B. Jeganathan, Jia Yu, Henan Zhang, Wei Ding, Jan M. van Deursen, Zhenkun Lou
Published 2018-07-01

In Vivo SILAC-Based Proteomics Reveals Phosphoproteome Changes during Mouse Skin Carcinogenesis

by Sara Zanivan, Alexander Meves, Kristina Behrendt, Erwin M. Schoof, Lisa J. Neilson, Jürgen Cox, Hao R. Tang, Gabriela Kalna, Janine H. van Ree, Jan M. van Deursen, Carol S. Trempus, Laura M. Machesky, Rune Linding, Sara A. Wickström, Reinhard Fässler, Matthias Mann
Published 2013-02-01