Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice[S]

by Changcheng Zhou, Nakesha King, Kwan Y. Chen, Jan L. Breslow
Published 2009-10-01

Hyperglycemic Ins2AkitaLdlr−/− mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease[S]

by Changcheng Zhou, Brian Pridgen, Nakesha King, Jinxian Xu, Jan L. Breslow
Published 2011-08-01

Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J × CASA /Rk intercross

by Ephraim Sehayek, Elizabeth M. Duncan, Hannah J. Yu, Lynn Petukhova, Jan L. Breslow
Published 2003-09-01

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism[S]

by Joshua J. Riegelhaupt, Marc P. Waase, Jeanne Garbarino, Daniel E. Cruz, Jan L. Breslow
Published 2010-05-01

Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

by Kara N. Maxwell, Raymond E. Soccio, Elizabeth M. Duncan, Ephraim Sehayek, Jan L. Breslow
Published 2003-11-01

STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC

by Jeanne Garbarino, Meihui Pan, Harvey F. Chin, Frederik W. Lund, Frederick R. Maxfield, Jan L. Breslow
Published 2012-12-01

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice

by Emanuel Voyiaziakis, Ira J. Goldberg, Andrew S. Plump, Edward M. Rubin, Jan L. Breslow, Li-Shin Huang
Published 1998-02-01

U-shape relationship between change in dietary cholesterol absorptionand plasma lipoprotein responsiveness and evidence for extreme interindividualvariation in dietary cholesterol...

by Ephraim Sehayek, Chithranjan Nath, Thomas Heinemann, Monnie McGee, Cynthia E. Seidman, Paul Samuel, Jan L. Breslow
Published 1998-12-01

ApoA-II maintains HDL levels in part by inhibition of hepatic lipase: studies in apoA-II and hepatic lipase double knockout mice

by Wei Weng, Neal A. Brandenburg, Shaobin Zhong, Joanna Halkias, Lin Wu, Xian-cheng Jiang, Alan Tall, Jan L. Breslow
Published 1999-06-01

Localization of the PE methylation pathway and SR-BI to the canalicular membrane

by Ephraim Sehayek, Rong Wang, Jennie G. Ono, Vadim S. Zinchuk, Elizabeth M. Duncan, Sarah Shefer, Dennis E. Vance, Meenakshisundaram Ananthanarayanan, Brian T. Chait, Jan L. Breslow
Published 2003-09-01

A complex plasma plant sterol locus on mouse chromosome 14 has at least two genes regulating intestinal sterol absorption

by Ephraim Sehayek, Yee Yan Fung, Hannah J. Yu, Jan Lembcke, Uta Ceglarek, Daniel Teupser, Joachim Thiery, Dieter Lutjohann, Klaus von Bergmann, Jan L. Breslow
Published 2006-10-01

Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprits⃞

by Ephraim Sehayek, Lee R. Hagey, Yee-Yan Fung, Elizabeth M. Duncan, Hannah J. Yu, Gösta Eggertsen, Ingemar Björkhem, Alan F. Hofmann, Jan L. Breslow
Published 2006-09-01

Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice

by Ephraim Sehayek, Jennie G. Ono, Elizabeth M. Duncan, Ashok K. Batta, Gerald Salen, Sarah Shefer, Lien B. Neguyen, Kan Yang, Martin Lipkin, Jan L. Breslow
Published 2001-08-01

Author Correction: Obesity and ethnicity alter gene expression in skin

by Jeanne M. Walker, Sandra Garcet, Jose O. Aleman, Christopher E. Mason, David Danko, Daniel Butler, Simone Zuffa, Jonathan R. Swann, James Krueger, Jan L. Breslow, Peter R. Holt
Published 2021-03-01

Phytosterolemia on the island of Kosrae

by Ephraim Sehayek, Hannah J. Yu, Klaus von Bergmann, Dieter Lutjohann, Markus Stoffel, Elizabeth M. Duncan, Laura Garcia-Naveda, Jacqueline Salit, Maude L. Blundell, Jeffrey M. Friedman, Jan L. Breslow
Published 2004-09-01

Fecal microbiota and bile acid interactions with systemic and adipose tissue metabolism in diet-induced weight loss of obese postmenopausal women

by José O. Alemán, Nicholas A. Bokulich, Jonathan R. Swann, Jeanne M. Walker, Joel Correa De Rosa, Thomas Battaglia, Adele Costabile, Alexandros Pechlivanis, Yupu Liang, Jan L. Breslow, Martin J. Blaser, Peter R. Holt
Published 2018-09-01

Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females

by Elizabeth R. De Oliveira e Silva, Margaret Kong, Zhihua Han, Catherine Starr, Elizabeth M. Kass, Suh-Hang Hank Juo, David Foster, Hayes M. Dansky, Martin Merkel, Katherine Cundey, Eliot A. Brinton, Jan L. Breslow, Jonathan D. Smith
Published 1999-07-01

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

by Jennifer K Lowe, Julian B Maller, Itsik Pe'er, Benjamin M Neale, Jacqueline Salit, Eimear E Kenny, Jessica L Shea, Ralph Burkhardt, J Gustav Smith, Weizhen Ji, Martha Noel, Jia Nee Foo, Maude L Blundell, Vita Skilling, Laura Garcia, Marcia L Sullivan, Heather E Lee, Anna Labek, Hope Ferdowsian, Steven B Auerbach, Richard P Lifton, Christopher Newton-Cheh, Jan L Breslow, Markus Stoffel, Mark J Daly, David M Altshuler, Jeffrey M Friedman
Published 2009-02-01