Deconvoluting heme biosynthesis to target blood-stage malaria parasites

by Paul A Sigala, Jan R Crowley, Jeffrey P Henderson, Daniel E Goldberg
Published 2015-07-01

The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking

by Jessie Zhang, Nicole Dudley-Rucker, Jan R. Crowley, Elvira Lopez-Perez, Marc Issandou, Jean E. Schaffer, Daniel S. Ory
Published 2004-02-01

Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli.

by Jeffrey P Henderson, Jan R Crowley, Jerome S Pinkner, Jennifer N Walker, Pablo Tsukayama, Walter E Stamm, Thomas M Hooton, Scott J Hultgren
Published 2009-02-01

Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Rese...

by Kaveri S. Parker, Jan R. Crowley, Alisa J. Stephens-Shields, Adrie van Bokhoven, M. Scott Lucia, H. Henry Lai, Gerald L. Andriole, Thomas M. Hooton, Chris Mullins, Jeffrey P. Henderson
Published 2016-05-01

Extracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.

by Joseph E Ippolito, Matthew W Brandenburg, Xia Ge, Jan R Crowley, Kristopher M Kirmess, Avik Som, D Andre D'Avignon, Jeffrey M Arbeit, Samuel Achilefu, Kevin E Yarasheski, Jeffrey Milbrandt
Published 2016-01-01

Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway

by Sarah E. Smith, Xiaoying Chen, Lindsey M. Brier, Jonathan R. Bumstead, Nicholas R. Rensing, Alison E. Ringel, Haewon Shin, Anna Oldenborg, Jan R. Crowley, Annie R. Bice, Krikor Dikranian, Joseph E. Ippolito, Marcia C. Haigis, Thomas Papouin, Guoyan Zhao, Michael Wong, Joseph P. Culver, Azad Bonni
Published 2020-12-01

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

by Ismail Sergin, Trent D. Evans, Xiangyu Zhang, Somashubhra Bhattacharya, Carl J. Stokes, Eric Song, Sahl Ali, Babak Dehestani, Karyn B. Holloway, Paul S. Micevych, Ali Javaheri, Jan R. Crowley, Andrea Ballabio, Joel D. Schilling, Slava Epelman, Conrad C. Weihl, Abhinav Diwan, Daping Fan, Mohamed A. Zayed, Babak Razani
Published 2017-06-01