Metabolic Cancer-Macrophage Crosstalk in the Tumor Microenvironment

by Kyra E. de Goede, Amber J. M. Driessen, Jan Van den Bossche
Published 2020-11-01

Macrophages, PPARs, and Cancer

by Jo A. Van Ginderachter, Kiavash Movahedi, Jan Van den Bossche, Patrick De Baetselier
Published 2008-01-01

Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy

by Matheus H W Crommentuijn, Sjoerd T T Schetters, Laura J W Kruijssen, Yvette van Kooyk, Ernesto Rodriguez, Jan Van den Bossche, Joke M M Den Haan
Published 2020-07-01

Myeloid Ezh2 Deficiency Limits Atherosclerosis Development

by Annette E. Neele, Hung-Jen Chen, Marion J. J. Gijbels, Marion J. J. Gijbels, Saskia van der Velden, Marten A. Hoeksema, Marten A. Hoeksema, Marieke C. S. Boshuizen, Jan Van den Bossche, Jan Van den Bossche, Anton T. Tool, Hanke L. Matlung, Timo K. van den Berg, Esther Lutgens, Esther Lutgens, Menno P. J. de Winther
Published 2021-01-01

Myeloid-Specific Acly Deletion Alters Macrophage Phenotype <i>In Vitro</i> and <i>In Vivo</i> without Affecting Tumor Growth

by Kyra E. de Goede, Sanne G. S. Verberk, Jeroen Baardman, Karl J. Harber, Yvette van Kooyk, Menno P. J. de Winther, Sjoerd T. T. Schetters, Jan Van den Bossche
Published 2021-06-01

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

by Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-09-01

Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling

by Martje N. Erkelens, Gera Goverse, Tanja Konijn, Rosalie Molenaar, Marieke R. Beijer, Jan Van den Bossche, Kyra E. de Goede, Sanne G. S. Verberk, Wouter J. de Jonge, Joke M. M. den Haan, Reina E. Mebius
Published 2020-03-01

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

by Jan Van den Bossche, Jeroen Baardman, Natasja A. Otto, Saskia van der Velden, Annette E. Neele, Susan M. van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C.S. Boshuizen, Mohamed Ahmed, Marten A. Hoeksema, Alex F. de Vos, Menno P.J. de Winther
Published 2016-10-01

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

by Sanne G. S. Verberk, Hendrik J. P. van der Zande, Jeroen Baardman, Kyra E. de Goede, Karl J. Harber, Karl J. Harber, Eelco D. Keuning, Joost M. Lambooij, Frank Otto, Anna Zawistowska-Deniziak, Anna Zawistowska-Deniziak, Helga E. de Vries, Menno P. J. de Winther, Bruno Guigas, Jan Van den Bossche
Published 2021-04-01

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.

by Mariëtte R Boon, Sjoerd A A van den Berg, Yanan Wang, Jan van den Bossche, Sofia Karkampouna, Matthias Bauwens, Marijke De Saint-Hubert, Geertje van der Horst, Slobodan Vukicevic, Menno P J de Winther, Louis M Havekes, J Wouter Jukema, Jouke T Tamsma, Gabri van der Pluijm, Ko Willems van Dijk, Patrick C N Rensen
Published 2013-01-01

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

by Jeroen Baardman, Sanne G.S. Verberk, Koen H.M. Prange, Michel van Weeghel, Saskia van der Velden, Dylan G. Ryan, Rob C.I. Wüst, Annette E. Neele, Dave Speijer, Simone W. Denis, Maarten E. Witte, Riekelt H. Houtkooper, Luke A. O’neill, Elena V. Knatko, Albena T. Dinkova-Kostova, Esther Lutgens, Menno P.J. de Winther, Jan Van den Bossche
Published 2018-11-01

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

by Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J.J. Gijbels, Marion J.J. Gijbels, Cindy P.P.A. van Roomen, Sharon G. Bernard, Wouter J. de Jonge, Inmaculada Rioja, Rab K. Prinjha, Huw D. Lewis, Palwinder K. Mander, Menno P.J. de Winther, Menno P.J. de Winther
Published 2019-10-01

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

by Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H. M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-12-01