Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteome

by John Y. Ng, Lies Boelen, Jason W. H. Wong
Published 2013-01-01

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations.

by Rebecca C Poulos, Yuen T Wong, Regina Ryan, Herbert Pang, Jason W H Wong
Published 2018-11-01

Identification of allosteric disulfides from labile bonds in X-ray structures

by Aster E. Pijning, Joyce Chiu, Reichelle X. Yeo, Jason W. H. Wong, Philip J. Hogg
Published 2018-01-01

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.

by Hu Fang, Jayne A Barbour, Rebecca C Poulos, Riku Katainen, Lauri A Aaltonen, Jason W H Wong
Published 2020-02-01

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

by Mahdi Zeraati, Aaron L. Moye, Jason W. H. Wong, Dilmi Perera, Mark J. Cowley, Daniel U. Christ, Tracy M. Bryan, Marcel E. Dinger
Published 2017-04-01

A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients

by Xiaoqiang Zhu, Xianglong Tian, Linhua Ji, Xinyu Zhang, Yingying Cao, Chaoqin Shen, Ye Hu, Jason W. H. Wong, Jing-Yuan Fang, Jie Hong, Haoyan Chen
Published 2021-02-01

The non-coding RNA landscape of human hematopoiesis and leukemia

by Adrian Schwarzer, Stephan Emmrich, Franziska Schmidt, Dominik Beck, Michelle Ng, Christina Reimer, Felix Ferdinand Adams, Sarah Grasedieck, Damian Witte, Sebastian Käbler, Jason W. H. Wong, Anushi Shah, Yizhou Huang, Razan Jammal, Aliaksandra Maroz, Mojca Jongen-Lavrencic, Axel Schambach, Florian Kuchenbauer, John E. Pimanda, Dirk Reinhardt, Dirk Heckl, Jan-Henning Klusmann
Published 2017-08-01

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

by Matthew Wong, Yuting Sun, Zhichao Xi, Giorgio Milazzo, Rebecca C. Poulos, Christoph Bartenhagen, Jessica L. Bell, Chelsea Mayoh, Nicholas Ho, Andrew E. Tee, Xiaoqiong Chen, Yang Li, Roberto Ciaccio, Pei Y. Liu, Chen C. Jiang, Qing Lan, Nisitha Jayatilleke, Belamy B. Cheung, Michelle Haber, Murray D. Norris, Xu D. Zhang, Glenn M. Marshall, Jenny Y. Wang, Stefan Hüttelmaier, Matthias Fischer, Jason W. H. Wong, Hongxi Xu, Giovanni Perini, Qihan Dong, Rani E. George, Tao Liu
Published 2019-07-01

Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes

by Ashwin Unnikrishnan, Elli Papaemmanuil, Dominik Beck, Nandan P. Deshpande, Arjun Verma, Ashu Kumari, Petter S. Woll, Laura A. Richards, Kathy Knezevic, Vashe Chandrakanthan, Julie A.I. Thoms, Melinda L. Tursky, Yizhou Huang, Zara Ali, Jake Olivier, Sally Galbraith, Austin G. Kulasekararaj, Magnus Tobiasson, Mohsen Karimi, Andrea Pellagatti, Susan R. Wilson, Robert Lindeman, Boris Young, Raj Ramakrishna, Christopher Arthur, Richard Stark, Philip Crispin, Jennifer Curnow, Pauline Warburton, Fernando Roncolato, Jacqueline Boultwood, Kevin Lynch, Sten Eirik W. Jacobsen, Ghulam J. Mufti, Eva Hellstrom-Lindberg, Marc R. Wilkins, Karen L. MacKenzie, Jason W.H. Wong, Peter J. Campbell, John E. Pimanda
Published 2017-07-01