Computational investigations into the origins of short-term biochemical memory in T cell activation.

by Jason W Locasale
Published 2007-01-01

Metabolomics reveals intratumor heterogeneity – Implications for precision medicine

by Xiaojing Liu, Jason W. Locasale
Published 2017-05-01

Metabolomics: insights into plant‐based diets

by Annamarie E Allen, Jason W Locasale
Published 2021-02-01

Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data.

by Jason W Locasale, Alejandro Wolf-Yadlin
Published 2009-08-01

Regulation of signal duration and the statistical dynamics of kinase activation by scaffold proteins.

by Jason W Locasale, Arup K Chakraborty
Published 2008-06-01

Metabolic landscape of the tumor microenvironment at single cell resolution

by Zhengtao Xiao, Ziwei Dai, Jason W. Locasale
Published 2019-08-01

Metabolism in the tumor microenvironment: insights from single-cell analysis

by Zhengtao Xiao, Jason W. Locasale, Ziwei Dai
Published 2020-01-01

Molecular features that predict the response to antimetabolite chemotherapies

by Mahya Mehrmohamadi, Seong Ho Jeong, Jason W. Locasale
Published 2017-10-01

Organization of enzyme concentration across the metabolic network in cancer cells.

by Neel S Madhukar, Marc O Warmoes, Jason W Locasale
Published 2015-01-01

Characterization of the Usage of the Serine Metabolic Network in Human Cancer

by Mahya Mehrmohamadi, Xiaojing Liu, Alexander A. Shestov, Jason W. Locasale
Published 2014-11-01

Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism

by Mahya Mehrmohamadi, Lucas K. Mentch, Andrew G. Clark, Jason W. Locasale
Published 2016-12-01

Interactions between epigenetics and metabolism in cancers

by Jihye eYun, Jared Lee Johnson, Christin L Hanigan, Jason W Locasale
Published 2012-11-01

Estimating relative changes of metabolic fluxes.

by Lei Huang, Dongsung Kim, Xiaojing Liu, Christopher R Myers, Jason W Locasale
Published 2014-11-01

Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

by Ziwei Dai, Samantha J. Mentch, Xia Gao, Sailendra N. Nichenametla, Jason W. Locasale
Published 2018-05-01

Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow

by Zheng Ser, Xia Gao, Christelle Johnson, Mahya Mehrmohamadi, Xiaojing Liu, Siqi Li, Jason W. Locasale
Published 2016-06-01

RRmix: A method for simultaneous batch effect correction and analysis of metabolomics data in the absence of internal standards.

by Stephen Salerno, Mahya Mehrmohamadi, Maria V Liberti, Muting Wan, Martin T Wells, James G Booth, Jason W Locasale
Published 2017-01-01

Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism

by Xia Gao, Katie Lee, Michael A. Reid, Sydney M. Sanderson, Chuping Qiu, Siqi Li, Juan Liu, Jason W. Locasale
Published 2018-03-01

Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification

by Inah Hwang, Hiroki Uchida, Ziwei Dai, Fei Li, Teresa Sanchez, Jason W. Locasale, Lewis C. Cantley, Hongwu Zheng, Jihye Paik
Published 2021-01-01

Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer

by Min Lu, Sydney M Sanderson, Amelia Zessin, Kathleen A Ashcraft, Lee W Jones, Mark W Dewhirst, Jason W Locasale, David S Hsu
Published 2018-11-01

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer

by Sunghee Park, Rachid Safi, Xiaojing Liu, Robert Baldi, Wen Liu, Juan Liu, Jason W. Locasale, Ching-yi Chang, Donald P. McDonnell
Published 2019-06-01