Human Brain Organoids to Decode Mechanisms of Microcephaly

by Elke Gabriel, Anand Ramani, Nazlican Altinisik, Jay Gopalakrishnan
Published 2020-05-01

Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes

by Anand Ramani, Aruljothi Mariappan, Marco Gottardo, Sunit Mandad, Henning Urlaub, Tomer Avidor-Reiss, Maria Riparbelli, Giuliano Callaini, Alain Debec, Regina Feederle, Jay Gopalakrishnan
Published 2018-12-01

Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila

by Jean-André Lapart, Marco Gottardo, Elisabeth Cortier, Jean-Luc Duteyrat, Céline Augière, Alain Mangé, Julie Jerber, Jérôme Solassol, Jay Gopalakrishnan, Joëlle Thomas, Bénédicte Durand
Published 2019-12-01

Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications

by Wei Liu, Paweł Stachura, Haifeng C. Xu, Nikkitha Umesh Ganesh, Fiona Cox, Ruifeng Wang, Karl S. Lang, Jay Gopalakrishnan, Dieter Häussinger, Bernhard Homey, Philipp A. Lang, Aleksandra A. Pandyra
Published 2020-02-01

Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length

by Xiangdong Zheng, Anand Ramani, Komal Soni, Marco Gottardo, Shuangping Zheng, Li Ming Gooi, Wenjing Li, Shan Feng, Aruljothi Mariappan, Arpit Wason, Per Widlund, Andrei Pozniakovsky, Ina Poser, Haiteng Deng, Guangshuo Ou, Maria Riparbelli, Callaini Giuliano, Anthony A. Hyman, Michael Sattler, Jay Gopalakrishnan, Haitao Li
Published 2016-06-01

RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

by Muhammad Farooq, Louise Lindbæk, Nicolai Krogh, Canan Doganli, Cecilie Keller, Maren Mönnich, André Brás Gonçalves, Srinivasan Sakthivel, Yuan Mang, Ambrin Fatima, Vivi Søgaard Andersen, Muhammad S. Hussain, Hans Eiberg, Lars Hansen, Klaus Wilbrandt Kjaer, Jay Gopalakrishnan, Lotte Bang Pedersen, Kjeld Møllgård, Henrik Nielsen, Shahid. M. Baig, Niels Tommerup, Søren Tvorup Christensen, Lars Allan Larsen
Published 2020-11-01