HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.

by Jean-Philippe Belzile, Ghislaine Duisit, Nicole Rougeau, Johanne Mercier, Andrés Finzi, Eric A Cohen
Published 2007-07-01

Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest.

by Jean-Philippe Belzile, Levon G Abrahamyan, Francine C A Gérard, Nicole Rougeau, Eric A Cohen
Published 2010-09-01

Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest.

by Francine C A Gérard, Ruifeng Yang, Bizhan Romani, Alexis Poisson, Jean-Philippe Belzile, Nicole Rougeau, Éric A Cohen
Published 2014-01-01