Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

by Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi
Published 2008-12-01

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.

by Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Ana Krtolica, Christian M Beauséjour, Simona Parrinello, J Graeme Hodgson, Koei Chin, Pierre-Yves Desprez, Judith Campisi
Published 2010-02-01

Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance

by Fei Chen, Qilai Long, Da Fu, Dexiang Zhu, Yan Ji, Liu Han, Boyi Zhang, Qixia Xu, Bingjie Liu, Yan Li, Shanshan Wu, Chen Yang, Min Qian, Jianmin Xu, Suling Liu, Liu Cao, Y. Eugene Chin, Eric W.-F. Lam, Jean-Philippe Coppé, Yu Sun
Published 2018-10-01

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors

by Imke H. Bartelink, Brendan Prideaux, Gregor Krings, Lisa Wilmes, Pei Rong Evelyn Lee, Pan Bo, Byron Hann, Jean-Philippe Coppé, Diane Heditsian, Lamorna Swigart-Brown, Ella F. Jones, Sergey Magnitsky, Ron J Keizer, Niels de Vries, Hilde Rosing, Nela Pawlowska, Scott Thomas, Mallika Dhawan, Rahul Aggarwal, Pamela N. Munster, Laura J. Esserman, Weiming Ruan, Alan H. B. Wu, Douglas Yee, Véronique Dartois, Radojka M. Savic, Denise M. Wolf, Laura van ’t Veer
Published 2017-09-01