Acute Myeloid Leukemia Chemo-Resistance Is Mediated by E-selectin Receptor CD162 in Bone Marrow Niches

by Johanna Erbani, Joshua Tay, Valerie Barbier, Jean-Pierre Levesque, Ingrid G. Winkler
Published 2020-07-01

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo.

by Yi Shen, Ingrid G Winkler, Valerie Barbier, Natalie A Sims, Jean Hendy, Jean-Pierre Lévesque
Published 2010-01-01

Engraftment Outcomes after HPC Co-Culture with Mesenchymal Stromal Cells and Osteoblasts

by Matthew M. Cook, Michael R. Doran, Katarina Kollar, Valerie Barbier, Ingrid G. Winkler, Jean-Pierre Levesque, Gary Brooke, Kerry Atkinson
Published 2013-09-01

Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner

by Kavita Bisht, Joshua Tay, Rebecca N. Wellburn, Crystal McGirr, Whitney Fleming, Bianca Nowlan, Valerie Barbier, Ingrid G. Winkler, Jean-Pierre Levesque
Published 2020-10-01

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

by Kylie A. Alexander, Hsu-Wen Tseng, Whitney Fleming, Beulah Jose, Marjorie Salga, Marjorie Salga, Irina Kulina, Susan M. Millard, Allison R. Pettit, François Genêt, François Genêt, Jean-Pierre Levesque
Published 2019-03-01

Peripheral denervation participates in heterotopic ossification in a spinal cord injury model.

by Charlotte Debaud, Marjorie Salga, Laurent Begot, Xavier Holy, Malha Chedik, Nicolas de l'Escalopier, Fréderic Torossian, Jean-Pierre Levesque, Jean-Jacques Lataillade, Marie-Caroline Le Bousse-Kerdilès, François Genêt
Published 2017-01-01

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

by Simranpreet Kaur, Anuj Sehgal, Andy C. Wu, Susan M. Millard, Lena Batoon, Cheyenne J. Sandrock, Michelle Ferrari-Cestari, Jean-Pierre Levesque, David A. Hume, Liza J. Raggatt, Allison R. Pettit
Published 2021-01-01

Neurogenic Heterotopic Ossifications Recapitulate Hematopoietic Stem Cell Niche Development Within an Adult Osteogenic Muscle Environment

by Dorothée Girard, Frédéric Torossian, Estelle Oberlin, Kylie A. Alexander, Jules Gueguen, Hsu-Wen Tseng, François Genêt, Jean-Jacques Lataillade, Marjorie Salga, Jean-Pierre Levesque, Marie-Caroline Le Bousse-Kerdilès, Sébastien Banzet
Published 2021-03-01

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

by Valerie Barbier, Johanna Erbani, Corrine Fiveash, Julie M. Davies, Joshua Tay, Michael R. Tallack, Jessica Lowe, John L. Magnani, Diwakar R. Pattabiraman, Andrew C. Perkins, Jessica Lisle, John E. J. Rasko, Jean-Pierre Levesque, Ingrid G. Winkler
Published 2020-04-01