Resolution of Complex Issues in Genome Regulation and Cancer Requires Non-Linear and Network-Based Thermodynamics

by Jekaterina Erenpreisa, Alessandro Giuliani
Published 2019-12-01

Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change.

by Masa Tsuchiya, Alessandro Giuliani, Midori Hashimoto, Jekaterina Erenpreisa, Kenichi Yoshikawa
Published 2016-01-01

Emergent Self-Organized Criticality in Gene Expression Dynamics: Temporal Development of Global Phase Transition Revealed in a Cancer Cell Line.

by Masa Tsuchiya, Alessandro Giuliani, Midori Hashimoto, Jekaterina Erenpreisa, Kenichi Yoshikawa
Published 2015-01-01

Meta-Analysis of Cancer Triploidy: Rearrangements of Genome Complements in Male Human Tumors Are Characterized by XXY Karyotypes

by Ninel M. Vainshelbaum, Pawel Zayakin, Regina Kleina, Alessandro Giuliani, Jekaterina Erenpreisa
Published 2019-08-01

Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells

by Anda Huna, Kristine Salmina, Elina Jascenko, Gunars Duburs, Inna Inashkina, Jekaterina Erenpreisa
Published 2011-01-01

Phylostratic Shift of Whole-Genome Duplications in Normal Mammalian Tissues towards Unicellularity Is Driven by Developmental Bivalent Genes and Reveals a Link to Cancer

by Olga V. Anatskaya, Alexander E. Vinogradov, Ninel M. Vainshelbaum, Alessandro Giuliani, Jekaterina Erenpreisa
Published 2020-11-01

The Cancer Aneuploidy Paradox: In the Light of Evolution

by Kristine Salmina, Anda Huna, Martins Kalejs, Dace Pjanova, Harry Scherthan, Mark S. Cragg, Jekaterina Erenpreisa
Published 2019-01-01

When Three Isn’t a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers

by Kristine Salmina, Bogdan I. Gerashchenko, Michael Hausmann, Ninel M. Vainshelbaum, Pawel Zayakin, Juris Erenpreiss, Talivaldis Freivalds, Mark S. Cragg, Jekaterina Erenpreisa
Published 2019-07-01

Heterochromatin Networks: Topology, Dynamics, and Function (a Working Hypothesis)

by Jekaterina Erenpreisa, Jekabs Krigerts, Kristine Salmina, Bogdan I. Gerashchenko, Talivaldis Freivalds, Reet Kurg, Ruth Winter, Matthias Krufczik, Pawel Zayakin, Michael Hausmann, Alessandro Giuliani
Published 2021-06-01

“Mitotic Slippage” and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres

by Kristine Salmina, Agnieszka Bojko, Inna Inashkina, Karolina Staniak, Magdalena Dudkowska, Petar Podlesniy, Felikss Rumnieks, Ninel M Vainshelbaum, Dace Pjanova, Ewa Sikora, Jekaterina Erenpreisa
Published 2020-04-01