Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

by Jason E. Comer, Olivier Escaffre, Natasha Neef, Trevor Brasel, Terry L. Juelich, Jennifer K. Smith, Jeanon Smith, Birte Kalveram, David D. Perez, Shane Massey, Lihong Zhang, Alexander N. Freiberg
Published 2019-02-01

STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV)

by Olivier Escaffre, Terry L. Juelich, Natasha Neef, Shane Massey, Jeanon Smith, Trevor Brasel, Jennifer K. Smith, Birte Kalveram, Lihong Zhang, David Perez, Tetsuro Ikegami, Alexander N. Freiberg, Jason E. Comer
Published 2021-07-01

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

by Brian B Gowen, Terry L Juelich, Eric J Sefing, Trevor Brasel, Jennifer K Smith, Lihong Zhang, Bersabeh Tigabu, Terence E Hill, Tatyana Yun, Colette Pietzsch, Yousuke Furuta, Alexander N Freiberg
Published 2013-01-01

Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model.

by José Peña, Jessica A Plante, Alda Celena Carillo, Kimberly K Roberts, Jennifer K Smith, Terry L Juelich, David W C Beasley, Alexander N Freiberg, Montiago X Labute, Pejman Naraghi-Arani
Published 2014-10-01

RIG-I enhanced interferon independent apoptosis upon Junin virus infection.

by Olga A Kolokoltsova, Ashley M Grant, Cheng Huang, Jennifer K Smith, Allison L Poussard, Bing Tian, Allan R Brasier, Clarence J Peters, Chien-Te Kent Tseng, Juan C de la Torre, Slobodan Paessler
Published 2014-01-01

Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model.

by Tetsuro Ikegami, Aaron Balogh, Shoko Nishiyama, Nandadeva Lokugamage, Tais B Saito, John C Morrill, Vinay Shivanna, Sabarish V Indran, Lihong Zhang, Jennifer K Smith, David Perez, Terry L Juelich, Igor Morozov, William C Wilson, Alexander N Freiberg, Juergen A Richt
Published 2017-01-01

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion.

by Frederic Vigant, Jihye Lee, Axel Hollmann, Lukas B Tanner, Zeynep Akyol Ataman, Tatyana Yun, Guanghou Shui, Hector C Aguilar, Dong Zhang, David Meriwether, Gleyder Roman-Sosa, Lindsey R Robinson, Terry L Juelich, Hubert Buczkowski, Sunwen Chou, Miguel A R B Castanho, Mike C Wolf, Jennifer K Smith, Ashley Banyard, Margaret Kielian, Srinivasa Reddy, Markus R Wenk, Matthias Selke, Nuno C Santos, Alexander N Freiberg, Michael E Jung, Benhur Lee
Published 2013-01-01