A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery.

by Jens Tiefenbach, Pamela R Moll, Meryl R Nelson, Chun Hu, Lilia Baev, Thomas Kislinger, Henry M Krause
Published 2010-03-01

Idebenone and coenzyme Q10 are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases

by Jens Tiefenbach, Lilia Magomedova, Jiabao Liu, Arkadiy A. Reunov, Ricky Tsai, Neena S. Eappen, Rebecca A. Jockusch, Corey Nislow, Carolyn L. Cummins, Henry M. Krause
Published 2018-09-01

The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.

by Keith I Pardee, Xiaohui Xu, Jeff Reinking, Anja Schuetz, Aiping Dong, Suya Liu, Rongguang Zhang, Jens Tiefenbach, Gilles Lajoie, Alexander N Plotnikov, Alexey Botchkarev, Henry M Krause, Aled Edwards
Published 2009-02-01

Correction: 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

by Robert J Evans, Katherine Pline, Catherine A Loynes, Sarah Needs, Maceler Aldrovandi, Jens Tiefenbach, Ewa Bielska, Rachel E Rubino, Christopher J Nicol, Robin C May, Henry M Krause, Valerie B O'Donnell, Stephen A Renshaw, Simon A Johnston
Published 2020-11-01

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

by Robert J Evans, Katherine Pline, Catherine A Loynes, Sarah Needs, Maceler Aldrovandi, Jens Tiefenbach, Ewa Bielska, Rachel E Rubino, Christopher J Nicol, Robin C May, Henry M Krause, Valerie B O'Donnell, Stephen A Renshaw, Simon A Johnston
Published 2019-03-01