Structure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia

by Sara-Teresa Méndez, Adriana Castillo-Villanueva, Karina Martínez-Mayorga, Horacio Reyes-Vivas, Jesús Oria-Hernández
Published 2019-08-01

Disulfiram as a novel inactivator of Giardia lamblia triosephosphate isomerase with antigiardial potential

by Adriana Castillo-Villanueva, Yadira Rufino-González, Sara-Teresa Méndez, Angélica Torres-Arroyo, Martha Ponce-Macotela, Mario Noé Martínez-Gordillo, Horacio Reyes-Vivas, Jesús Oria-Hernández
Published 2017-12-01

RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene

by Jaime Marcial-Quino, Saúl Gómez-Manzo, Francisco Fierro, Yadira Rufino-González, Daniel Ortega-Cuellar, Edgar Sierra-Palacios, America Vanoye-Carlo, Abigail González-Valdez, Angélica Torres-Arroyo, Jesús Oria-Hernández, Horacio Reyes-Vivas
Published 2017-11-01

The nuclear receptor FXR, but not LXR, up-regulates bile acid transporter expression in non-alcoholic fatty liver disease

by Nancy E. Aguilar-Olivos, Daniel Carrillo-Córdova, Jesús Oria-Hernández, Vicente Sánchez-Valle, Guadalupe Ponciano-Rodríguez, Manuel Ramírez-Jaramillo, Fredy Chablé-Montero, Norberto C. Chávez-Tapia, Misael Uribe, Nahum Méndez-Sánchez, MD, MSc, PhD, FACG, AGAF
Published 2015-07-01

Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.

by Gloria Hernández-Alcántara, Alfredo Torres-Larios, Sergio Enríquez-Flores, Itzhel García-Torres, Adriana Castillo-Villanueva, Sara T Méndez, Ignacio de la Mora-de la Mora, Saúl Gómez-Manzo, Angélica Torres-Arroyo, Gabriel López-Velázquez, Horacio Reyes-Vivas, Jesús Oria-Hernández
Published 2013-01-01

Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies

by Alejandra Vázquez-Raygoza, Lucia Cano-González, Israel Velázquez-Martínez, Pedro Josué Trejo-Soto, Rafael Castillo, Alicia Hernández-Campos, Francisco Hernández-Luis, Jesús Oria-Hernández, Adriana Castillo-Villanueva, Claudia Avitia-Domínguez, Erick Sierra-Campos, Mónica Valdez-Solana, Alfredo Téllez-Valencia
Published 2017-11-01

Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.

by Ignacio de la Mora-de la Mora, Alfredo Torres-Larios, Sergio Enríquez-Flores, Sara-Teresa Méndez, Adriana Castillo-Villanueva, Saúl Gómez-Manzo, Gabriel López-Velázquez, Jaime Marcial-Quino, Angélica Torres-Arroyo, Itzhel García-Torres, Horacio Reyes-Vivas, Jesús Oria-Hernández
Published 2015-01-01

The Stability of G6PD Is Affected by Mutations with Different Clinical Phenotypes

by Saúl Gómez-Manzo, Jessica Terrón-Hernández, Ignacio De la Mora-De la Mora, Abigail González-Valdez, Jaime Marcial-Quino, Itzhel García-Torres, America Vanoye-Carlo, Gabriel López-Velázquez, Gloria Hernández-Alcántara, Jesús Oria-Hernández, Horacio Reyes-Vivas, Sergio Enríquez-Flores
Published 2014-11-01

Biochemical Analysis of Two Single Mutants that Give Rise to a Polymorphic G6PD A-Double Mutant

by Edson Jiovany Ramírez-Nava, Daniel Ortega-Cuellar, Hugo Serrano-Posada, Abigail González-Valdez, America Vanoye-Carlo, Beatriz Hernández-Ochoa, Edgar Sierra-Palacios, Jessica Hernández-Pineda, Eduardo Rodríguez-Bustamante, Roberto Arreguin-Espinosa, Jesús Oria-Hernández, Horacio Reyes-Vivas, Jaime Marcial-Quino, Saúl Gómez-Manzo
Published 2017-10-01

Proteomics: a tool to develop novel diagnostic methods and unravel molecular mechanisms of pediatric diseases

by Angélica Torres-Arroyo, Arturo Ruiz-Lara, Adriana Castillo-Villanueva, Sara Teresa Méndez-Cruz, Sara Elvia Espinosa-Padilla, Francisco Javier Espinosa-Rosales, Flora Zarate-Mondragón, Roberto Cervantes-Bustamante, Vanessa Bosch-Canto, Iris Vizzuett-López, Juan Carlos Ordaz-Fávila, Jesús Oria-Hernández, Horacio Reyes-Vivas
Published 2017-05-01