Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of En...

by Jessica Oi-Ling Tsang, Jie Zhou, Xiaoyu Zhao, Cun Li, Zijiao Zou, Feifei Yin, Shuofeng Yuan, Man-Lung Yeung, Hin Chu, Jasper Fuk-Woo Chan
Published 2021-01-01

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in <i>Enterovirus</i>-Infected Cells

by Zijiao Zou, Jessica Oi-Ling Tsang, Bingpeng Yan, Kenn Ka-Heng Chik, Chris Chun-Yiu Chan, Jianli Cao, Ronghui Liang, Kaiming Tang, Feifei Yin, Zi-Wei Ye, Hin Chu, Jasper Fuk-Woo Chan, Shuofeng Yuan, Kwok-Yung Yuen
Published 2020-07-01

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

by Shuofeng Yuan, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Ronghui Liang, Jianli Cao, Kaiming Tang, Jian-Piao Cai, Zi-Wei Ye, Feifei Yin, Kelvin Kai-Wang To, Hin Chu, Dong-Yan Jin, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan
Published 2020-06-01

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory stud...

by Hin Chu, PhD, Jasper Fuk-Woo Chan, MD, Terrence Tsz-Tai Yuen, BA, Huiping Shuai, PhD, Shuofeng Yuan, PhD, Yixin Wang, MPhil, Bingjie Hu, MPhil, Cyril Chik-Yan Yip, PhD, Jessica Oi-Ling Tsang, BSc, Xiner Huang, BSc, Yue Chai, MPhil, Dong Yang, MPhil, Yuxin Hou, MPhil, Kenn Ka-Heng Chik, MMedSc, Xi Zhang, BSc, Agnes Yim-Fong Fung, BSc, Hoi-Wah Tsoi, MPhil, Jian-Piao Cai, BSc, Wan-Mui Chan, PhD, Jonathan Daniel Ip, MSc, Allen Wing-Ho Chu, MSc, Jie Zhou, PhD, David Christopher Lung, FRCPath, Kin-Hang Kok, PhD, Kelvin Kai-Wang To, MD, Owen Tak-Yin Tsang, FRCP, Kwok-Hung Chan, PhD, Kwok-Yung Yuen, ProfMD
Published 2020-05-01