Strategies for the Discovery and Development of Anti-Diabetic Drugs from the Natural Products of Traditional Medicines

by Ji-Ming Ye, Stanley M.H.
Published 2013-05-01

Involvement of the Autophagy-ER Stress Axis in High Fat/Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease

by Xiu Zhou, Sherouk Fouda, Dongli Li, Kun Zhang, Ji-Ming Ye
Published 2020-08-01

Characterization of the Therapeutic Profile of Albiflorin for the Metabolic Syndrome

by Xiu Zhou, Xiu Zhou, Xiu Zhou, Sherouk Fouda, Xiao-Yi Zeng, Dongli Li, Kun Zhang, Kun Zhang, Jun Xu, Ji-Ming Ye, Ji-Ming Ye
Published 2019-10-01

Matrine Protects Against MCD-Induced Development of NASH via Upregulating HSP72 and Downregulating mTOR in a Manner Distinctive From Metformin

by Ali Mahzari, Songpei Li, Xiu Zhou, Xiu Zhou, Dongli Li, Sherouk Fouda, Majid Alhomrani, Wala Alzahrani, Stephen R. Robinson, Ji-Ming Ye, Ji-Ming Ye
Published 2019-04-01

TanshinoneIIA and cryptotanshinone protect against hypoxia-induced mitochondrial apoptosis in H9c2 cells.

by Hyou-Ju Jin, Xiao-Liang Xie, Ji-Ming Ye, Chun-Guang Li
Published 2013-01-01

Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21.

by Eunjung Jo, Songpei Li, Qingning Liang, Xinmei Zhang, Hao Wang, Terence P Herbert, Trisha A Jenkins, Aimin Xu, Ji-Ming Ye
Published 2017-01-01

Hepatic FoxO1 acetylation is involved in oleanolic acid-induced memory of glycemic control: novel findings from Study 2.

by Xiu Zhou, Xiao-Yi Zeng, Hao Wang, Songpei Li, Eunjung Jo, Charlie C L Xue, Minjia Tan, Juan C Molero, Ji-Ming Ye
Published 2014-01-01

Activation of AMPK by bitter melon triterpenoids involves CaMKKβ.

by Tristan J Iseli, Nigel Turner, Xiao-Yi Zeng, Gregory J Cooney, Edward W Kraegen, Sheng Yao, Yang Ye, David E James, Ji-Ming Ye
Published 2013-01-01

Oleanolic acid reduces hyperglycemia beyond treatment period with Akt/FoxO1-induced suppression of hepatic gluconeogenesis in type-2 diabetic mice.

by Xiao-Yi Zeng, Yi-Ping Wang, James Cantley, Tristan J Iseli, Juan Carlos Molero, Bronwyn D Hegarty, Edward W Kraegen, Yang Ye, Ji-Ming Ye
Published 2012-01-01

Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.

by Lu-Ping Ren, Stanley M H Chan, Xiao-Yi Zeng, D Ross Laybutt, Tristan J Iseli, Ruo-Qiong Sun, Edward W Kraegen, Gregory J Cooney, Nigel Turner, Ji-Ming Ye
Published 2012-01-01

NPY neuron-specific Y2 receptors regulate adipose tissue and trabecular bone but not cortical bone homeostasis in mice.

by Yan-Chuan Shi, Shu Lin, Iris P L Wong, Paul A Baldock, Aygul Aljanova, Ronaldo F Enriquez, Lesley Castillo, Natalie F Mitchell, Ji-Ming Ye, Lei Zhang, Laurence Macia, Ernie Yulyaningsih, Amy D Nguyen, Sabrina J Riepler, Herbert Herzog, Amanda Sainsbury
Published 2010-01-01