Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.

by Weizhong Chen, Hongyuan Zhang, Yifei Zhang, Yu Wang, Jianhua Gan, Quanjiang Ji
Published 2019-10-01

Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1

by Baixing Wu, Shichen Su, Deepak P. Patil, Hehua Liu, Jianhua Gan, Samie R. Jaffrey, Jinbiao Ma
Published 2018-01-01

OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice

by Kangxi Du, Qiang Luo, Liufan Yin, Jiabing Wu, Yuhao Liu, Jianhua Gan, Aiwu Dong, Wen-Hui Shen
Published 2020-11-01

Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa.

by Jingru Zhao, Xiang Yu, Miao Zhu, Huaping Kang, Jinbiao Ma, Min Wu, Jianhua Gan, Xin Deng, Haihua Liang
Published 2016-04-01

The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment

by Bing Liu, Yuhao Liu, Baihui Wang, Qiang Luo, Jinlei Shi, Jianhua Gan, Wen-Hui Shen, Yu Yu, Aiwu Dong
Published 2019-07-01

Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa.

by Dan Wang, Weizhong Chen, Shanqing Huang, Yafeng He, Xichun Liu, Qingyuan Hu, Tianbiao Wei, Hong Sang, Jianhua Gan, Hao Chen
Published 2017-07-01

Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1

by Jiayi Chen, Li Liu, Chenjiang You, Jiaqi Gu, Wenjie Ruan, Lu Zhang, Jianhua Gan, Chunyang Cao, Ying Huang, Xuemei Chen, Jinbiao Ma
Published 2018-09-01

Unique 5'-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X.

by Yiqing Chen, Jing Zhang, Hehua Liu, Yanqing Gao, Xuhang Li, Lina Zheng, Ruixue Cui, Qingqing Yao, Liang Rong, Jixi Li, Zhen Huang, Jinbiao Ma, Jianhua Gan
Published 2017-02-01

Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases

by Zhengyang Li, Long Li, Yingyi Huo, Zijun Chen, Yu Zhao, Jing Huang, Shuling Jian, Zhen Rong, Di Wu, Jianhua Gan, Xiaojian Hu, Jixi Li, Xue-Wei Xu
Published 2020-06-01

Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

by Yiqing Chen, Hehua Liu, Chun Yang, Yanqing Gao, Xiang Yu, Xi Chen, Ruixue Cui, Lina Zheng, Suhua Li, Xuhang Li, Jinbiao Ma, Zhen Huang, Jixi Li, Jianhua Gan
Published 2019-01-01

Crystal structure of an RNA-cleaving DNAzyme

by Hehua Liu, Xiang Yu, Yiqing Chen, Jing Zhang, Baixing Wu, Lina Zheng, Phensinee Haruehanroengra, Rui Wang, Suhua Li, Jinzhong Lin, Jixi Li, Jia Sheng, Zhen Huang, Jinbiao Ma, Jianhua Gan
Published 2017-12-01

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation

by Zijun Chen, Zhengyang Li, Xiaojian Hu, Feiyan Xie, Siyun Kuang, Bowen Zhan, Wenqing Gao, Xiangjun Chen, Siqi Gao, Yang Li, Yongming Wang, Feng Qian, Chen Ding, Jianhua Gan, Chaoneng Ji, Xue‐Wei Xu, Zheng Zhou, Jinqing Huang, Housheng Hansen He, Jixi Li
Published 2020-07-01