Lovastatin inhibits VEGFR and AKT activation: synergistic cytotoxicity in combination with VEGFR inhibitors.

by Tong T Zhao, Diane Trinh, Christina L Addison, Jim Dimitroulakos
Published 2010-09-01

Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.

by Laurie Ma, Nima Niknejad, Ivan Gorn-Hondermann, Khalil Dayekh, Jim Dimitroulakos
Published 2012-01-01

Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer

by Mohamed S. Hasim, Carolyn Nessim, Patrick J. Villeneuve, Barbara C. Vanderhyden, Jim Dimitroulakos
Published 2018-08-01

miR-105 inhibits prostate tumour growth by suppressing CDK6 levels.

by D Rice Honeywell, Miguel A Cabrita, Huijun Zhao, Jim Dimitroulakos, Christina L Addison
Published 2013-01-01

Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways ana Activating Transcription Factor 3

by Carly St. Germain, Nima Niknejad, Laurie Ma, Kyla Garbuio, Tsonwin Hai, Jim Dimitroulakos
Published 2010-07-01

Does metformin usage improve survival in head and neck squamous cell carcinoma? A population-based study

by Alexandra E. Quimby, Nicole L. Lebo, Rebecca Griffiths, Stephen Hall, Jim Dimitroulakos, Stephanie Johnson-Obaseki
Published 2018-12-01

Correction to: HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours

by Jason K. Wasserman, Ryan Rourke, Bibianna Purgina, Lisa Caulley, Jim Dimitroulakos, Martin Corsten, Stephanie Johnson-Obaseki
Published 2018-08-01

Microarray and Biochemical Analysis of Lovastatin-induced Apoptosis of Squamous Cell Carcinomas

by Jim Dimitroulakos, Wilson H. Marhin, Jason Tokunaga, Jonathan Irish, Patrick Gullane, Linda Z. Penn, Suzanne Kamel-Reid
Published 2002-01-01

Induction of Activating Transcription Factor 3 Is Associated with Cisplatin Responsiveness in Non–Small Cell Lung Carcinoma Cells

by Jair Bar, Mohamed S. Hasim, Tabassom Baghai, Nima Niknejad, Theodore J. Perkins, David J. Stewart, Harmanjatinder S. Sekhon, Patrick J. Villeneuve, Jim Dimitroulakos
Published 2016-09-01

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells

by Andrew Sulaiman, Sarah McGarry, Jason Chambers, Emil Al-Kadi, Alexandra Phan, Li Li, Karan Mediratta, Jim Dimitroulakos, Christina Addison, Xuguang Li, Lisheng Wang
Published 2020-08-01

Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer.

by Grant A Howe, Bin Xiao, Huijun Zhao, Khalid N Al-Zahrani, Mohamed S Hasim, James Villeneuve, Harmanjatinder S Sekhon, Glenwood D Goss, Luc A Sabourin, Jim Dimitroulakos, Christina L Addison
Published 2016-01-01

Dual inhibition of Wnt and Yes‐associated protein signaling retards the growth of triple‐negative breast cancer in both mesenchymal and epithelial states

by Andrew Sulaiman, Sarah McGarry, Li Li, Deyong Jia, Sarah Ooi, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao, Guang Ji, Haiyan Song, Suresh Gadde, Xuguang Li, Lisheng Wang
Published 2018-04-01