Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

by Anna Schliermann, Joachim Nickel
Published 2018-10-01

Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchy...

by Janina Belka, Joachim Nickel, Dirk G. Kurth
Published 2019-06-01

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3).

by Uschi Diestel, Marcus Resch, Kathrin Meinhardt, Sigrid Weiler, Tina V Hellmann, Thomas D Mueller, Joachim Nickel, Jutta Eichler, Yves A Muller
Published 2013-01-01

Utilizing BMP-2 muteins for treatment of multiple myeloma.

by Axel Seher, Charlotte Lagler, Thorsten Stühmer, Urs Dietmar Achim Müller-Richter, Alexander Christian Kübler, Walter Sebald, Thomas Dieter Müller, Joachim Nickel
Published 2017-01-01

The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent.

by Charlotte Lagler, Mohamed El-Mesery, Alexander Christian Kübler, Urs Dietmar Achim Müller-Richter, Thorsten Stühmer, Joachim Nickel, Thomas Dieter Müller, Harald Wajant, Axel Seher
Published 2017-01-01

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2.

by Elisa Degenkolbe, Jana König, Julia Zimmer, Maria Walther, Carsten Reißner, Joachim Nickel, Frank Plöger, Jelena Raspopovic, James Sharpe, Katarina Dathe, Jacqueline T Hecht, Stefan Mundlos, Sandra C Doelken, Petra Seemann
Published 2013-01-01

Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP–2 and Enhanced Bone Regeneration

by Kai Stuckensen, José M. Lamo-Espinosa, Emma Muiños-López, Purificación Ripalda-Cemboráin, Tania López-Martínez, Elena Iglesias, Gloria Abizanda, Ion Andreu, María Flandes-Iparraguirre, Juan Pons-Villanueva, Reyes Elizalde, Joachim Nickel, Andrea Ewald, Uwe Gbureck, Felipe Prósper, Jürgen Groll, Froilán Granero-Moltó
Published 2019-09-01

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN.

by Petra Seemann, Anja Brehm, Jana König, Carsten Reissner, Sigmar Stricker, Pia Kuss, Julia Haupt, Stephanie Renninger, Joachim Nickel, Walter Sebald, Jay C Groppe, Frank Plöger, Jens Pohl, Mareen Schmidt-von Kegler, Maria Walther, Ingmar Gassner, Cristina Rusu, Andreas R Janecke, Katarina Dathe, Stefan Mundlos
Published 2009-11-01