Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer

by Daniele Bano, Jochen H.M. Prehn
Published 2018-04-01

Metabolic Targeting of Breast Cancer Cells With the 2-Deoxy-D-Glucose and the Mitochondrial Bioenergetics Inhibitor MDIVI-1

by Federico Lucantoni, Federico Lucantoni, Heiko Dussmann, Heiko Dussmann, Jochen H. M. Prehn, Jochen H. M. Prehn
Published 2018-09-01

Anti-apoptotic BCL-2 family proteins in acute neural injury

by UJVAL eANILKUMAR, Jochen H. M. Prehn
Published 2014-09-01

Expanding the substantial interactome of NEMO using protein microarrays.

by Beau J Fenner, Michael Scannell, Jochen H M Prehn
Published 2010-01-01

A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/...

by Karen S. Coughlan, Luise Halang, Ina Woods, Jochen H. M. Prehn
Published 2016-09-01

Integrating Colon Cancer Microarray Data: Associating Locus-Specific Methylation Groups to Gene Expression-Based Classifications

by Ana Barat, Heather J. Ruskin, Annette T. Byrne, Jochen H. M. Prehn
Published 2015-11-01

Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation

by Sinéad Kinsella, Michael Fichtner, Orla Watters, Hans-Georg König, Jochen H. M. Prehn
Published 2018-05-01

BH3 Mimetics Reactivate Autophagic Cell Death in Anoxia-Resistant Malignant Glioma Cells

by Holger Hetschko, Valerie Voss, Christian Senft, Volker Seifert, Jochen H.M. Prehn, Donat Kögel
Published 2008-08-01

Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca2+-Induced Neuronal Injury

by Beatrice D’Orsi, Beatrice D’Orsi, Natalia Niewidok, Heiko Düssmann, Jochen H. M. Prehn
Published 2021-10-01

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

by Hans-Georg König, Karen S. Coughlan, Sinéad Kinsella, Bridget A. Breen, Jochen H.M. Prehn
Published 2014-10-01

Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects.

by Barbara Köhler, Sergio Anguissola, Caoimhin G Concannon, Markus Rehm, Donat Kögel, Jochen H M Prehn
Published 2008-07-01

Charge profile analysis reveals that activation of pro-apoptotic regulators Bax and Bak relies on charge transfer mediated allosteric regulation.

by Crina-Maria Ionescu, Radka Svobodová Vařeková, Jochen H M Prehn, Heinrich J Huber, Jaroslav Koča
Published 2012-01-01

Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions.

by Niamh M C Connolly, Beatrice D'Orsi, Naser Monsefi, Heinrich J Huber, Jochen H M Prehn
Published 2016-01-01

Resistance to Cell Death in Mucinous Colorectal Cancer—A Review

by Emer O’Connell, Ian S. Reynolds, Deborah A. McNamara, John P. Burke, Jochen H. M. Prehn
Published 2021-03-01

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

by Viktorija Juric, Heiko Düssmann, Martine L. M. Lamfers, Jochen H. M. Prehn, Markus Rehm, Brona M. Murphy
Published 2021-05-01

The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia

by Sean Quinlan, Paula Merino-Serrais, Paula Merino-Serrais, Alessandra Di Grande, Heiko Dussmann, Jochen H. M. Prehn, Jochen H. M. Prehn, Tríona Ní Chonghaile, David C. Henshall, David C. Henshall, David C. Henshall, Eva M. Jimenez-Mateos, Eva M. Jimenez-Mateos
Published 2019-07-01

Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform.

by Anna Matveeva, Michael Fichtner, Katherine McAllister, Christopher McCann, Marc Sturrock, Daniel B Longley, Jochen H M Prehn
Published 2019-09-01

System-based approaches as prognostic tools for glioblastoma

by Manuela Salvucci, Zaitun Zakaria, Steven Carberry, Amanda Tivnan, Volker Seifert, Donat Kögel, Brona M. Murphy, Jochen H. M. Prehn
Published 2019-11-01

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.

by Ujval Anilkumar, Petronela Weisova, Jasmin Schmid, Tytus Bernas, Heinrich J Huber, Heiko Düssmann, Niamh M C Connolly, Jochen H M Prehn
Published 2017-01-01

Correction: Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model

by Martin Crivello, Marion C. Hogg, Elisabeth Jirström, Luise Halang, Ina Woods, Megan Rayner, Karen S. Coughlan, Sebastian A. Lewandowski, Jochen H. M. Prehn
Published 2020-05-01