Chromatin landscape dictates HSF binding to target DNA elements.

by Michael J Guertin, John T Lis
Published 2010-09-01

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

by Iris Jonkers, Hojoong Kwak, John T Lis
Published 2014-04-01

New Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization

by Abdullah Ozer, John M Pagano, John T Lis
Published 2014-01-01

Accurate prediction of inducible transcription factor binding intensities in vivo.

by Michael J Guertin, André L Martins, Adam Siepel, John T Lis
Published 2012-01-01

Cdk9 regulates a promoter-proximal checkpoint to modulate RNA polymerase II elongation rate in fission yeast

by Gregory T. Booth, Pabitra K. Parua, Miriam Sansó, Robert P. Fisher, John T. Lis
Published 2018-02-01

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

by William S Kruesi, Leighton J Core, Colin T Waters, John T Lis, Barbara J Meyer
Published 2013-06-01

Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer.

by H Hans Salamanca, Marc A Antonyak, Richard A Cerione, Hua Shi, John T Lis
Published 2014-01-01

Transcriptional response to stress is pre-wired by promoter and enhancer architecture

by Anniina Vihervaara, Dig Bijay Mahat, Michael J. Guertin, Tinyi Chu, Charles G. Danko, John T. Lis, Lea Sistonen
Published 2017-08-01

Defining the Status of RNA Polymerase at Promoters

by Leighton J. Core, Joshua J. Waterfall, Daniel A. Gilchrist, David C. Fargo, Hojoong Kwak, Karen Adelman, John T. Lis
Published 2012-10-01

GAGA factor maintains nucleosome-free regions and has a role in RNA polymerase II recruitment to promoters.

by Nicholas J Fuda, Michael J Guertin, Sumeet Sharma, Charles G Danko, André L Martins, Adam Siepel, John T Lis
Published 2015-03-01

Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.

by Michael J Guertin, Xuesen Zhang, Lynne Anguish, Sohyoung Kim, Lyuba Varticovski, John T Lis, Gordon L Hager, Scott A Coonrod
Published 2014-09-01

RAPID-SELEX for RNA aptamers.

by Kylan Szeto, David R Latulippe, Abdullah Ozer, John M Pagano, Brian S White, David Shalloway, John T Lis, Harold G Craighead
Published 2013-01-01

Genome-wide control of RNA polymerase II activity by cohesin.

by Cheri A Schaaf, Hojoong Kwak, Amanda Koenig, Ziva Misulovin, David W Gohara, Audrey Watson, Yanjiao Zhou, John T Lis, Dale Dorsett
Published 2013-03-01

Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions.

by John M Pagano, Hojoong Kwak, Colin T Waters, Rebekka O Sprouse, Brian S White, Abdullah Ozer, Kylan Szeto, David Shalloway, Harold G Craighead, John T Lis
Published 2014-01-01

Pol II Docking and Pausing at Growth and Stress Genes in C. elegans

by Colin S. Maxwell, William S. Kruesi, Leighton J. Core, Nicole Kurhanewicz, Colin T. Waters, Caitlin L. Lewarch, Igor Antoshechkin, John T. Lis, Barbara J. Meyer, L. Ryan Baugh
Published 2014-02-01

Chromatin Architecture of the Pitx2 Locus Requires CTCF- and Pitx2-Dependent Asymmetry that Mirrors Embryonic Gut Laterality

by Ian C. Welsh, Hojoong Kwak, Frances L. Chen, Melissa Werner, Lindsay S. Shopland, Charles G. Danko, John T. Lis, Min Zhang, James F. Martin, Natasza A. Kurpios
Published 2015-10-01

Discovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surface.

by Hsien-Wei Meng, John M Pagano, Brian S White, Yoshiko Toyoda, Irene M Min, Harold G Craighead, David Shalloway, John T Lis, Kai Xiao, Moonsoo M Jin
Published 2014-01-01

RNA-DNA Differences Are Generated in Human Cells within Seconds after RNA Exits Polymerase II

by Isabel X. Wang, Leighton J. Core, Hojoong Kwak, Lauren Brady, Alan Bruzel, Lee McDaniel, Allison L. Richards, Ming Wu, Christopher Grunseich, John T. Lis, Vivian G. Cheung
Published 2014-03-01

Distinct properties and functions of CTCF revealed by a rapidly inducible degron system

by Jing Luan, Guanjue Xiang, Pablo Aurelio Gómez-García, Jacob M. Tome, Zhe Zhang, Marit W. Vermunt, Haoyue Zhang, Anran Huang, Cheryl A. Keller, Belinda M. Giardine, Yu Zhang, Yemin Lan, John T. Lis, Melike Lakadamyali, Ross C. Hardison, Gerd A. Blobel
Published 2021-02-01

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML

by Yue Zhao, Qi Liu, Pankaj Acharya, Kristy R. Stengel, Quanhu Sheng, Xiaofan Zhou, Hojoong Kwak, Melissa A. Fischer, James E. Bradner, Stephen A. Strickland, Sanjay R. Mohan, Michael R. Savona, Bryan J. Venters, Ming-Ming Zhou, John T. Lis, Scott W. Hiebert
Published 2016-08-01