Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed gliobl...

by David Mills, Patrick Yung Wen, Jordi A Rodon, Warren Mason, Joseph T Beck, John DeGroot, Valerie Donnet, Mona El-Hashimy, Mark Rosenthal
Published 2020-10-01

Buparlisib plus carboplatin or lomustine in patients with recurrent glioblastoma: a phase Ib/II, open-label, multicentre, randomised study

by David Mills, Hui Gan, Jeffrey Raizer, Patrick Yung Wen, Warren Mason, John DeGroot, Valerie Donnet, Mona El-Hashimy, Mark Rosenthal, Paul M Clement, Mario Campone, Miguel J Gil-Gil, Olivier Chinot, Ahmed Idbaih, Estela Pineda
Published 2020-10-01

Molecular subtypes of glioblastoma are relevant to lower grade glioma.

by Xiaowei Guan, Jaime Vengoechea, Siyuan Zheng, Andrew E Sloan, Yanwen Chen, Daniel J Brat, Brian Patrick O'Neill, John de Groot, Shlomit Yust-Katz, Wai-Kwan Alfred Yung, Mark L Cohen, Kenneth D Aldape, Steven Rosenfeld, Roeland G W Verhaak, Jill S Barnholtz-Sloan
Published 2014-01-01

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [¹⁸F]FAZA PET <i>In Vivo</i>

by Seth T. Gammon, Federica Pisaneschi, Madhavi L. Bandi, Melinda G. Smith, Yuting Sun, Yi Rao, Florian Muller, Franklin Wong, John De Groot, Jeffrey Ackroyd, Osama Mawlawi, Michael A. Davies, Y.N. Vashisht Gopal, M. Emilia Di Francesco, Joseph R. Marszalek, Mark Dewhirst, David Piwnica-Worms
Published 2019-11-01

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

by Yasaman Barekatain, Jeffrey J. Ackroyd, Victoria C. Yan, Sunada Khadka, Lin Wang, Ko-Chien Chen, Anton H. Poral, Theresa Tran, Dimitra K. Georgiou, Kenisha Arthur, Yu-Hsi Lin, Nikunj Satani, Elliot S. Ballato, Eliot I. Behr, Ana C. deCarvalho, Roel G. W. Verhaak, John de Groot, Jason T. Huse, John M. Asara, Raghu Kalluri, Florian L. Muller
Published 2021-07-01