Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

by Rabab Nasrallah, Kathy Knezevic, Thuan Thai, Shane R. Thomas, Berthold Göttgens, Georges Lacaud, Valerie Kouskoff, John E. Pimanda
Published 2015-07-01

Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure.

by Luke B Hesson, Vibha Patil, Mathew A Sloane, Andrea C Nunez, Jia Liu, John E Pimanda, Robyn L Ward
Published 2013-01-01

High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice

by Tata Nageswara Rao, Jonathan Marks-Bluth, Jessica Sullivan, Manoj K. Gupta, Vashe Chandrakanthan, Simon R. Fitch, Katrin Ottersbach, Young C. Jang, Xianhua Piao, Rohit N. Kulkarni, Thomas Serwold, John E. Pimanda, Amy J. Wagers
Published 2015-05-01

The non-coding RNA landscape of human hematopoiesis and leukemia

by Adrian Schwarzer, Stephan Emmrich, Franziska Schmidt, Dominik Beck, Michelle Ng, Christina Reimer, Felix Ferdinand Adams, Sarah Grasedieck, Damian Witte, Sebastian Käbler, Jason W. H. Wong, Anushi Shah, Yizhou Huang, Razan Jammal, Aliaksandra Maroz, Mojca Jongen-Lavrencic, Axel Schambach, Florian Kuchenbauer, John E. Pimanda, Dirk Reinhardt, Dirk Heckl, Jan-Henning Klusmann
Published 2017-08-01

Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys.

by Quintin Lee, Matthew P Padula, Natalia Pinello, Simon H Williams, Matthew B O'Rourke, Marcilio Jorge Fumagalli, Joseph D Orkin, Renhua Song, Babak Shaban, Ori Brenner, John E Pimanda, Wolfgang Weninger, William Marciel de Souza, Amanda D Melin, Justin J-L Wong, Marcus J Crim, Sébastien Monette, Ben Roediger, Christopher J Jolly
Published 2020-01-01

Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes

by Ashwin Unnikrishnan, Elli Papaemmanuil, Dominik Beck, Nandan P. Deshpande, Arjun Verma, Ashu Kumari, Petter S. Woll, Laura A. Richards, Kathy Knezevic, Vashe Chandrakanthan, Julie A.I. Thoms, Melinda L. Tursky, Yizhou Huang, Zara Ali, Jake Olivier, Sally Galbraith, Austin G. Kulasekararaj, Magnus Tobiasson, Mohsen Karimi, Andrea Pellagatti, Susan R. Wilson, Robert Lindeman, Boris Young, Raj Ramakrishna, Christopher Arthur, Richard Stark, Philip Crispin, Jennifer Curnow, Pauline Warburton, Fernando Roncolato, Jacqueline Boultwood, Kevin Lynch, Sten Eirik W. Jacobsen, Ghulam J. Mufti, Eva Hellstrom-Lindberg, Marc R. Wilkins, Karen L. MacKenzie, Jason W.H. Wong, Peter J. Campbell, John E. Pimanda
Published 2017-07-01

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

by Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell
Published 2014-10-01