Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing

by Jinia Lilianty, John F. Bateman, Shireen R. Lamandé
Published 2021-10-01

Maintaining mRNA integrity during decalcification of mineralized tissues.

by Daniele Belluoccio, Lynn Rowley, Christopher B Little, John F Bateman
Published 2013-01-01

Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing

by Louise H.W. Kung, Lisa Sampurno, Christopher B. Little, Shireen R. Lamandé, John F. Bateman
Published 2021-01-01

WARP interacts with collagen VI-containing microfibrils in the pericellular matrix of human chondrocytes.

by Uwe Hansen, Justin M Allen, Rachel White, Cathleen Moscibrocki, Peter Bruckner, John F Bateman, Jamie Fitzgerald
Published 2012-01-01

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

by Jinia Lilianty, Yudha Nur Patria, Edouard G. Stanley, Andrew G. Elefanty, John F. Bateman, Shireen R. Lamandé
Published 2020-05-01

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line

by Sara Howden, Hani Hosseini Far, Ali Motazedian, Andrew G. Elefanty, Edouard G. Stanley, Shireen R. Lamandé, John F. Bateman
Published 2019-07-01

bfb, a novel ENU-induced blebs mutant resulting from a missense mutation in Fras1.

by Kerry A Miller, Christopher T Gordon, Megan F Welfare, Georgina Caruana, John F Bertram, John F Bateman, Peter G Farlie
Published 2013-01-01

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

by Yudha Nur Patria, Jinia Lilianty, Andrew G. Elefanty, Edouard G. Stanley, Tanya Labonne, John F. Bateman, Shireen R. Lamandé
Published 2020-01-01

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

by Hani Hosseini Far, Yudha Nur Patria, Ali Motazedian, Andrew G. Elefanty, Edouard G. Stanley, Shireen R. Lamandé, John F. Bateman
Published 2019-05-01

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRP...

by Yudha Nur Patria, Tayla Stenta, Jinia Lilianty, Lynn Rowley, Edouard G. Stanley, Andrew G. Elefanty, John F. Bateman, Shireen R. Lamandé
Published 2020-10-01

Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis

by Louise H. W. Kung, Lorna Mullan, Jamie Soul, Ping Wang, Kazutoshi Mori, John F. Bateman, Michael D. Briggs, Raymond P. Boot-Handford
Published 2019-09-01

CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A

by Louise H.W. Kung, Lisa Sampurno, Kathryn M. Yammine, Alison Graham, Penny McDonald, John F. Bateman, Matthew D. Shoulders, Shireen R. Lamandé
Published 2020-10-01

Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy.

by Trevor L Cameron, Katrina M Bell, Liliana Tatarczuch, Eleanor J Mackie, M Helen Rajpar, Ben T McDermott, Raymond P Boot-Handford, John F Bateman
Published 2011-01-01

XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease.

by Trevor L Cameron, Katrina M Bell, Irma L Gresshoff, Lisa Sampurno, Lorna Mullan, Joerg Ermann, Laurie H Glimcher, Raymond P Boot-Handford, John F Bateman
Published 2015-09-01

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease.

by Katarzyna A Piróg, Ella P Dennis, Claire L Hartley, Robert M Jackson, Jamie Soul, Jean-Marc Schwartz, John F Bateman, Raymond P Boot-Handford, Michael D Briggs
Published 2019-07-01

Identification of Two Independent <i>COL5A1</i> Variants in Dogs with Ehlers–Danlos Syndrome

by Anina Bauer, John F. Bateman, Shireen R. Lamandé, Eric Hanssen, Shannon G.M. Kirejczyk, Mark Yee, Ali Ramiche, Vidyha Jagannathan, Monika Welle, Tosso Leeb, Fiona L. Bateman
Published 2019-09-01

Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome.

by Kerry A Miller, Casey J Ah-Cann, Megan F Welfare, Tiong Y Tan, Kate Pope, Georgina Caruana, Mary-Louise Freckmann, Ravi Savarirayan, John F Bertram, Michael S Dobbie, John F Bateman, Peter G Farlie
Published 2013-08-01

Targeted induction of endoplasmic reticulum stress induces cartilage pathology.

by M Helen Rajpar, Ben McDermott, Louise Kung, Rachel Eardley, Lynette Knowles, Mel Heeran, David J Thornton, Richard Wilson, John F Bateman, Richard Poulsom, Peter Arvan, Karl E Kadler, Michael D Briggs, Raymond P Boot-Handford
Published 2009-10-01

Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function.

by Kwok Yeung Tsang, Danny Chan, Deborah Cheslett, Wilson C W Chan, Chi Leong So, Ian G Melhado, Tori W Y Chan, Kin Ming Kwan, Ernst B Hunziker, Yoshihiko Yamada, John F Bateman, Kenneth M C Cheung, Kathryn S E Cheah
Published 2007-03-01