Human Cytomegalovirus Manipulation of Latently Infected Cells

by John H. Sinclair, Matthew B. Reeves
Published 2013-11-01

Bromodomain Inhibitors as Therapeutics for Herpesvirus-Related Disease: All BETs Are Off?

by Ian J. Groves, John H. Sinclair, Mark R. Wills
Published 2020-07-01

HCMV Antivirals and Strategies to Target the Latent Reservoir

by Marianne R. Perera, Mark R. Wills, John H. Sinclair
Published 2021-05-01

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cel...

by Sarah E. Jackson, George X. Sedikides, Georgina Okecha, Emma L. Poole, John H. Sinclair, Mark R. Wills
Published 2017-06-01

A Virally Encoded DeSUMOylase Activity Is Required for Cytomegalovirus Reactivation from Latency

by Emma L. Poole, Verity G. Kew, Jonathan C.H. Lau, Matthew J. Murray, Thomas Stamminger, John H. Sinclair, Matthew B. Reeves
Published 2018-07-01

Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

by Benjamin A. Krishna, Emma L. Poole, Sarah E. Jackson, Martine J. Smit, Mark R. Wills, John H. Sinclair, Michael J. Imperiale
Published 2017-12-01

Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies

by Timo W. M. De Groof, Elizabeth G. Elder, Eleanor Y. Lim, Raimond Heukers, Nick D. Bergkamp, Ian J. Groves, Mark Wills, John H. Sinclair, Martine J. Smit
Published 2021-07-01

Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation

by Sarah E. Jackson, Kevin C. Chen, Ian J. Groves, George X. Sedikides, Amar Gandhi, Charlotte J. Houldcroft, Emma L. Poole, Inmaculada Montanuy, Gavin M. Mason, Georgina Okecha, Matthew B. Reeves, John H. Sinclair, Mark R. Wills
Published 2021-04-01