Pharmacological Inhibition and Activation of the Ca²⁺ Activated Cl⁻ Channel TMEM16A

by Raquel Centeio, Inês Cabrita, Roberta Benedetto, Khaoula Talbi, Jiraporn Ousingsawat, Rainer Schreiber, John K. Sullivan, Karl Kunzelmann
Published 2020-04-01

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways

by Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Esther Trueblood, Esther Trueblood, Kelly Hensley, Kelly Hensley, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
Published 2019-02-01