Interleukin 23 promotes hepatocellular carcinoma metastasis via NF-kappa B induced matrix metalloproteinase 9 expression.

by Jian Li, George Lau, Leilei Chen, Yun-Fei Yuan, Jun Huang, John M Luk, Dan Xie, Xin-Yuan Guan
Published 2012-01-01

miR-122 targets pyruvate kinase M2 and affects metabolism of hepatocellular carcinoma.

by Angela M Liu, Zhi Xu, Felix H Shek, Kwong-Fai Wong, Nikki P Lee, Ronnie T Poon, Jinfei Chen, John M Luk
Published 2014-01-01

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression.

by Jian Li, George Ka-Kit Lau, Leilei Chen, Sui-sui Dong, Hui-Yao Lan, Xiao-Ru Huang, Yan Li, John M Luk, Yun-Fei Yuan, Xin-yuan Guan
Published 2011-01-01

Anti-cadherin-17 antibody modulates beta-catenin signaling and tumorigenicity of hepatocellular carcinoma.

by Yonggang Wang, Felix H Shek, Kwong F Wong, Ling Xiao Liu, Xiao Qian Zhang, Yi Yuan, Ester Khin, Mei-Yu Hu, Jian Hua Wang, Ronnie T P Poon, Wanjin Hong, Nikki P Lee, John M Luk
Published 2013-01-01

Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma.

by Irena Ivanovska, Chunsheng Zhang, Angela M Liu, Kwong F Wong, Nikki P Lee, Patrick Lewis, Ulrike Philippar, Dimple Bansal, Carolyn Buser, Martin Scott, Mao Mao, Ronnie T P Poon, Sheung Tat Fan, Michele A Cleary, John M Luk, Hongyue Dai
Published 2011-01-01

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

by Mary McMahon, Adrian Contreras, Mikael Holm, Tamayo Uechi, Craig M Forester, Xiaming Pang, Cody Jackson, Meredith E Calvert, Bin Chen, David A Quigley, John M Luk, R Kate Kelley, John D Gordan, Ryan M Gill, Scott C Blanchard, Davide Ruggero
Published 2019-09-01

Genomic predictors for recurrence patterns of hepatocellular carcinoma: model derivation and validation.

by Ji Hoon Kim, Bo Hwa Sohn, Hyun-Sung Lee, Sang-Bae Kim, Jeong Eun Yoo, Yun-Yong Park, Woojin Jeong, Sung Sook Lee, Eun Sung Park, Ahmed Kaseb, Baek Hui Kim, Wan Bae Kim, Jong Eun Yeon, Kwan Soo Byun, In-Sun Chu, Sung Soo Kim, Xin Wei Wang, Snorri S Thorgeirsson, John M Luk, Koo Jeong Kang, Jeonghoon Heo, Young Nyun Park, Ju-Seog Lee
Published 2014-12-01

Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.

by John R Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Ke Hao, Eugene Chudin, Hunter B Fraser, Joshua Millstein, Mark Ferguson, Christine Suver, Irena Ivanovska, Martin Scott, Ulrike Philippar, Dimple Bansal, Zhan Zhang, Julja Burchard, Ryan Smith, Danielle Greenawalt, Michele Cleary, Jonathan Derry, Andrey Loboda, James Watters, Ronnie T P Poon, Sheung T Fan, Chun Yeung, Nikki P Y Lee, Justin Guinney, Cliona Molony, Valur Emilsson, Carolyn Buser-Doepner, Jun Zhu, Stephen Friend, Mao Mao, Peter M Shaw, Hongyue Dai, John M Luk, Eric E Schadt
Published 2011-01-01