Allele-specific methylation occurs at genetic variants associated with complex disease.

by John N Hutchinson, Towfique Raj, Jes Fagerness, Eli Stahl, Fernando T Viloria, Alexander Gimelbrant, Johanna Seddon, Mark Daly, Andrew Chess, Robert Plenge
Published 2014-01-01

Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers

by Zhihui Wang, Mulong Du, Qianyu Yuan, Yichen Guo, John N. Hutchinson, Li Su, Yinan Zheng, Jun Wang, Lorelei A. Mucci, Xihong Lin, Lifang Hou, David C. Christiani
Published 2020-03-01

Empirical comparison of reduced representation bisulfite sequencing and Infinium BeadChip reproducibility and coverage of DNA methylation in humans

by Juan J. Carmona, William P. Accomando, Alexandra M. Binder, John N. Hutchinson, Lorena Pantano, Benedetta Izzi, Allan C. Just, Xihong Lin, Joel Schwartz, Pantel S. Vokonas, Sami S. Amr, Andrea A. Baccarelli, Karin B. Michels
Published 2017-04-01

Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

by Peiyan Ni, Haneul Noh, Zhicheng Shao, Qian Zhu, Youxin Guan, Joshua J. Park, Fatima Arif, James M. Park, Chiderah Abani, Cameron Beaudreault, Joy S. Park, Elizabeth Berry, Alexander Moghadam, Patric Stanton, John N. Hutchinson, Bill Andrews, Clare Faux, John Parnevelas, Leonard M. Eisenberg, Kyungjoon Park, Vadim Y. Bolshakov, Sangmi Chung
Published 2019-06-01