A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition

by Shojiro Kitajima, Wendi Sun, Kian Leong Lee, Jolene Caifeng Ho, Seiichi Oyadomari, Takashi Okamoto, Hisao Masai, Lorenz Poellinger, Hiroyuki Kato
Published 2021-02-01

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells

by Jian Han, Jia Li, Jolene Caifeng Ho, Grace Sushin Chia, Hiroyuki Kato, Sudhakar Jha, Henry Yang, Lorenz Poellinger, Kian Leong Lee
Published 2017-06-01

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4

by Yanli Liu, Su Qin, Tsai-Yu Chen, Ming Lei, Shilpa S. Dhar, Jolene Caifeng Ho, Aiping Dong, Peter Loppnau, Yanjun Li, Min Gyu Lee, Jinrong Min
Published 2019-01-01

Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway.

by Jolene Caifeng Ho, Lissa Nurrul Abdullah, Qing You Pang, Sudhakar Jha, Edward Kai-Hua Chow, Henry Yang, Hiroyuki Kato, Lorenz Poellinger, Jun Ueda, Kian Leong Lee
Published 2017-01-01