Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits.

by Kristoffer Søberg, Tore Jahnsen, Torbjørn Rognes, Bjørn S Skålhegg, Jon K Laerdahl
Published 2013-01-01

Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reti...

by Thea Bismo Strøm, Kristian Tveten, Jon K. Laerdahl, Trond P. Leren
Published 2014-01-01

Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform.

by Natalia Berges, Meh Sameen Nawaz, Tuva Børresdatter Dahl, Lars Hagen, Magnar Bjørås, Jon K Laerdahl, Ingrun Alseth
Published 2019-01-01

Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones.

by Hanne Korvald, Anne Margrethe Mølstad Moe, F Henning Cederkvist, Bernd Thiede, Jon K Laerdahl, Magnar Bjørås, Ingrun Alseth
Published 2011-01-01

Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB.

by Seetha V Balasingham, Ephrem Debebe Zegeye, Håvard Homberset, Marie L Rossi, Jon K Laerdahl, Vilhelm A Bohr, Tone Tønjum
Published 2012-01-01

Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors

by Øystein L. Holla, Jamie Cameron, Kristian Tveten, Thea Bismo Str⊘m, Knut Erik Berge, Jon K. Laerdahl, Trond P. Leren
Published 2011-10-01

The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.

by Cathrine Fladeby, Erik Sebastian Vik, Jon K Laerdahl, Christine Gran Neurauter, Julie E Heggelund, Eirik Thorgaard, Pernille Strøm-Andersen, Magnar Bjørås, Bjørn Dalhus, Ingrun Alseth
Published 2012-01-01

Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA).

by Kristoffer Søberg, Anja C V Larsen, Mandy Diskar, Paul H Backe, Magnar Bjørås, Tore Jahnsen, Jon K Laerdahl, Torbjørn Rognes, Friedrich W Herberg, Bjørn S Skålhegg
Published 2012-01-01

Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.

by Johannes R Hov, Verena Keitel, Jon K Laerdahl, Lina Spomer, Eva Ellinghaus, Abdou ElSharawy, Espen Melum, Kirsten M Boberg, Thomas Manke, Tobias Balschun, Christoph Schramm, Annika Bergquist, Tobias Weismüller, Daniel Gotthardt, Christian Rust, Liesbet Henckaerts, Clive M Onnie, Rinse K Weersma, Martina Sterneck, Andreas Teufel, Heiko Runz, Adolf Stiehl, Cyriel Y Ponsioen, Cisca Wijmenga, Morten H Vatn, IBSEN Study Group, Pieter C F Stokkers, Severine Vermeire, Christopher G Mathew, Benedicte A Lie, Ulrich Beuers, Michael P Manns, Stefan Schreiber, Erik Schrumpf, Dieter Häussinger, Andre Franke, Tom H Karlsen
Published 2010-08-01