Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus.

by Cedric Leyrat, Max Renner, Karl Harlos, Jonathan M Grimes
Published 2013-01-01

Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription efficiency in Pneumovirinae

by Cedric Leyrat, Max Renner, Karl Harlos, Juha T Huiskonen, Jonathan M Grimes
Published 2014-05-01

Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies Its Role in Cell Entry

by Kamel El Omari, Oleg Iourin, Karl Harlos, Jonathan M. Grimes, David I. Stuart
Published 2013-01-01

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

by Gundeep Kaur, Soni Kaundal, Srajan Kapoor, Jonathan M. Grimes, Juha T. Huiskonen, Krishan Gopal Thakur
Published 2018-07-01

Detection of a fourth orbivirus non-structural protein.

by Mourad Belhouchet, Fauziah Mohd Jaafar, Andrew E Firth, Jonathan M Grimes, Peter P C Mertens, Houssam Attoui
Published 2011-01-01

The structure of an RNAi polymerase links RNA silencing and transcription.

by Paula S Salgado, Minni R L Koivunen, Eugene V Makeyev, Dennis H Bamford, David I Stuart, Jonathan M Grimes
Published 2006-12-01

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein

by Max Renner, Mattia Bertinelli, Cédric Leyrat, Guido C Paesen, Laura Freitas Saraiva de Oliveira, Juha T Huiskonen, Jonathan M Grimes
Published 2016-02-01

The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

by Stephen C Graham, L Peter Sarin, Mohammad W Bahar, Reg A Myers, David I Stuart, Dennis H Bamford, Jonathan M Grimes
Published 2011-06-01

Rhabdovirus matrix protein structures reveal a novel mode of self-association.

by Stephen C Graham, René Assenberg, Olivier Delmas, Anil Verma, Alireza Gholami, Chiraz Talbi, Raymond J Owens, David I Stuart, Jonathan M Grimes, Hervé Bourhy
Published 2008-12-01

Structure and function of A41, a vaccinia virus chemokine binding protein.

by Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes
Published 2008-01-01

The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA

by Sina Wittmann, Max Renner, Beth R. Watts, Oliver Adams, Miles Huseyin, Carlo Baejen, Kamel El Omari, Cornelia Kilchert, Dong-Hyuk Heo, Tea Kecman, Patrick Cramer, Jonathan M. Grimes, Lidia Vasiljeva
Published 2017-04-01

Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins

by Max Renner, Wanwisa Dejnirattisai, Loïc Carrique, Itziar Serna Martin, Dimple Karia, Serban L. Ilca, Shu F. Ho, Abhay Kotecha, Jeremy R. Keown, Juthathip Mongkolsapaya, Gavin R. Screaton, Jonathan M. Grimes
Published 2021-02-01

Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.

by Luigi De Colibus, Xiangxi Wang, Aloys Tijsma, Johan Neyts, John A B Spyrou, Jingshan Ren, Jonathan M Grimes, Gerhard Puerstinger, Pieter Leyssen, Elizabeth E Fry, Zihe Rao, David I Stuart
Published 2015-10-01

Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence.

by Carlos Maluquer de Motes, Samantha Cooray, Hongwei Ren, Gabriel M F Almeida, Kieran McGourty, Mohammad W Bahar, David I Stuart, Jonathan M Grimes, Stephen C Graham, Geoffrey L Smith
Published 2011-12-01

Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.

by Stephen C Graham, Mohammad W Bahar, Samantha Cooray, Ron A-J Chen, Daniel M Whalen, Nicola G A Abrescia, David Alderton, Raymond J Owens, David I Stuart, Geoffrey L Smith, Jonathan M Grimes
Published 2008-08-01

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

by Kamel El Omari, Sai Li, Abhay Kotecha, Thomas S. Walter, Eduardo A. Bignon, Karl Harlos, Pentti Somerharju, Felix De Haas, Daniel K. Clare, Mika Molin, Felipe Hurtado, Mengqiu Li, Jonathan M. Grimes, Dennis H. Bamford, Nicole D. Tischler, Juha T. Huiskonen, David I. Stuart, Elina Roine
Published 2019-02-01