The Role of Type I IFNs in Influenza: Antiviral Superheroes or Immunopathogenic Villains?

by Wenxin Wu, Jordan P. Metcalf
Published 2020-06-01

Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.

by Wenxin Wu, Wei Zhang, J Leland Booth, Jordan P Metcalf
Published 2012-01-01

IRF7 Is Required for the Second Phase Interferon Induction during Influenza Virus Infection in Human Lung Epithelia

by Wenxin Wu, Wei Zhang, Lili Tian, Brent R. Brown, Matthew S. Walters, Jordan P. Metcalf
Published 2020-03-01

Anthrax Edema and Lethal Toxins Differentially Target Human Lung and Blood Phagocytes

by Vineet I. Patel, J. Leland Booth, Mikhail Dozmorov, Brent R. Brown, Jordan P. Metcalf
Published 2020-07-01

Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2.

by Marybeth Langer, Alanson W Girton, Narcis I Popescu, Tarea Burgett, Jordan P Metcalf, K Mark Coggeshall
Published 2018-01-01

Regulation of influenza virus replication by Wnt/β-catenin signaling.

by Sunil More, Xiaoyun Yang, Zhengyu Zhu, Gayan Bamunuarachchi, Yujie Guo, Chaoqun Huang, Keith Bailey, Jordan P Metcalf, Lin Liu
Published 2018-01-01

Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-γ protection to influenza virus in mouse

by Wenxin Wu, Lili Tian, Wei Zhang, J. Leland Booth, Erola Ainsua-Enrich, Susan Kovats, Brent R. Brown, Jordan P. Metcalf
Published 2021-04-01

Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway.

by Marybeth Langer, Alexander Malykhin, Kenichiro Maeda, Kaushik Chakrabarty, Kelly S Williamson, Christa L Feasley, Christopher M West, Jordan P Metcalf, K Mark Coggeshall
Published 2008-01-01

RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection In Vivo

by Wenxin Wu, Xiaoqiu Wang, Wei Zhang, Lili Tian, J. Leland Booth, Elizabeth S. Duggan, Sunil More, Lin Liu, Mikhail Dozmorov, Jordan P. Metcalf
Published 2018-01-01

RIG-I overexpression decreases mortality of cigarette smoke exposed mice during influenza A virus infection

by Xiaoqiu Wang, Wenxin Wu, Wei Zhang, J. Leland Booth, Elizabeth S. Duggan, Lili Tian, Sunil More, Yan D. Zhao, Ravindranauth N. Sawh, Lin Liu, Ming-Hui Zou, Jordan P. Metcalf
Published 2017-09-01