Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease

by Maria V. Fernández, Maria V. Fernández, John Budde, John Budde, Jorge L. Del-Aguila, Jorge L. Del-Aguila, Laura Ibañez, Laura Ibañez, Yuetiva Deming, Yuetiva Deming, Oscar Harari, Oscar Harari, Joanne Norton, Joanne Norton, John C. Morris, John C. Morris, Alison M. Goate, NIA-LOAD family study group, NCRAD, Carlos Cruchaga, Carlos Cruchaga
Published 2018-04-01

Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

by Taylor J. Maxwell, Chris Corcoran, Jorge L. del-Aguila, John P. Budde, Yuetiva Deming, Carlos Cruchaga, Alison M. Goate, John S. K. Kauwe, Alzheimer’s Disease Neuroimaging Initiative
Published 2018-08-01

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

by Laura Ibanez, Umber Dube, Benjamin Saef, John Budde, Kathleen Black, Alexandra Medvedeva, Jorge L. Del-Aguila, Albert A. Davis, Joel S. Perlmutter, Oscar Harari, Bruno A. Benitez, Carlos Cruchaga
Published 2017-11-01

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

by Jorge L. Del-Aguila, Bruno A. Benitez, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Fabiana H. G. Farias, Maria Victoria Fernández, Laura Ibanez, Shan Jiang, Richard J. Perrin, Nigel J. Cairns, John C. Morris, Oscar Harari, Carlos Cruchaga
Published 2019-05-01

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

by Zeran Li, Jorge L. Del-Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, The Dominantly Inherited Alzheimer Network (DIAN), Joseph D. Dougherty, Jin-Moo Lee, John C. Morris, Randall J. Bateman, Celeste M. Karch, Carlos Cruchaga, Oscar Harari
Published 2018-06-01

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

by Jorge L. Del-Aguila, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Maria Victoria Fernandez, Laura Ibanez, Joseph Bradley, Fengxian Wang, Kristy Bergmann, Richard Davenport, John C. Morris, David M. Holtzman, Richard J. Perrin, Bruno A. Benitez, Joseph Dougherty, Carlos Cruchaga, Oscar Harari
Published 2019-08-01