Overcoming Chimeric Antigen Receptor (CAR) Modified T-Cell Therapy Limitations in Multiple Myeloma

by Estefanía García-Guerrero, Belén Sierro-Martínez, Jose Antonio Pérez-Simón
Published 2020-06-01

The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens

by Jose-Ignacio Rodriguez-Barbosa, Pascal Schneider, Luis Graca, Leo Bühler, Jose-Antonio Perez-Simon, Maria-Luisa del Rio
Published 2020-05-01

A conditional mouse mutant in the tumor suppressor SdhD gene unveils a link between p21(WAF1/Cip1) induction and mitochondrial dysfunction.

by Africa Millán-Uclés, Blanca Díaz-Castro, Paula García-Flores, Alicia Báez, José Antonio Pérez-Simón, José López-Barneo, José I Piruat
Published 2014-01-01

The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor.

by Estefanía García-Guerrero, José Antonio Pérez-Simón, Luis Ignacio Sánchez-Abarca, Irene Díaz-Moreno, Miguel A De la Rosa, Antonio Díaz-Quintana
Published 2016-01-01

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis

by Mauricio Sarmiento Maldonado, Pablo Ramírez Villanueva, Pablo Bertín Cortes-Monroy, Veronica Jara Arias, Katherine Soto Donoso, Pablo Uribe Gonzalez, Mauricio Ocqueteau Tachini, Jose Antonio Perez-Simón
Published 2017-12-01

PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche

by Guillermo López-Ruano, Rodrigo Prieto-Bermejo, Teresa L. Ramos, Laura San-Segundo, Luis Ignacio Sánchez-Abarca, Fermín Sánchez-Guijo, José Antonio Pérez-Simón, Jesús Sánchez-Yagüe, Marcial Llanillo, Ángel Hernández-Hernández
Published 2015-10-01

Human Bone Marrow Stromal Cells Differentiate into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice

by Luis Ignacio Sánchez-Abarca, Emiliano Hernández-Galilea M.D., Rebeca Lorenzo, Carmen Herrero, Almudena Velasco, Soraya Carrancio, Teresa Caballero-Velázquez, José Ignacio Rodríguez-Barbosa, Marta Parrilla, Consuelo Del Cañizo, Jesús San Miguel, José Aijón, José Antonio Pérez-Simón M.D., Ph.D.
Published 2015-12-01

Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases

by Ana Belén Guisado-Gil, Manuela Aguilar-Guisado, Germán Peñalva, José Antonio Lepe, Ildefonso Espigado, Eduardo Rodríguez-Arbolí, José González-Campos, Nancy Rodríguez-Torres, María Isabel Montero-Cuadrado, José Francisco Falantes-González, Juan Luis Reguera-Ortega, María Victoria Gil-Navarro, José Molina, José-Antonio Pérez-Simón, José Miguel Cisneros
Published 2021-01-01

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/...

by Belen Lopez-Millan, Rafael Diaz de la Guardia, Heleia Roca-Ho, Eduardo Anguita, Abul B. M. M. K. Islam, Damia Romero-Moya, Cristina Prieto, Francisco Gutierrez-Agüera, Jose Antonio Bejarano-Garcia, Jose Antonio Perez-Simon, Paula Costales, Montse Rovira, Pedro Marín, Silvia Menendez, Mar Iglesias, Jose Luis Fuster, Alvaro Urbano-Ispizua, Fernando Anjos-Afonso, Clara Bueno, Pablo Menendez
Published 2018-09-01