Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA.

by Oscar Quintana-Bustamante, Sara Fañanas-Baquero, Israel Orman, Raul Torres, Philippe Duchateau, Laurent Poirot, Agnès Gouble, Juan A Bueren, Jose C Segovia
Published 2019-01-01

Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo.

by Oscar Quintana-Bustamante, Esther Grueso, Ramon Garcia-Escudero, Elvira Arza, Alberto Alvarez-Barrientos, Isabel Fabregat, Maria Garcia-Bravo, Nestor W Meza, Jose C Segovia
Published 2012-01-01

The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy

by David García-Bernal, David García-Bernal, Mariano García-Arranz, Mariano García-Arranz, Rosa M. Yáñez, Rosa M. Yáñez, Rosa M. Yáñez, Rosario Hervás-Salcedo, Rosario Hervás-Salcedo, Rosario Hervás-Salcedo, Alfonso Cortés, Alfonso Cortés, María Fernández-García, María Fernández-García, María Fernández-García, Miriam Hernando-Rodríguez, Miriam Hernando-Rodríguez, Miriam Hernando-Rodríguez, Óscar Quintana-Bustamante, Óscar Quintana-Bustamante, Óscar Quintana-Bustamante, Juan A. Bueren, Juan A. Bueren, Juan A. Bueren, Damián García-Olmo, Damián García-Olmo, Jose M. Moraleda, Jose M. Moraleda, José C. Segovia, José C. Segovia, José C. Segovia, Agustín G. Zapata, Agustín G. Zapata
Published 2021-03-01

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

by Zita Garate, Oscar Quintana-Bustamante, Ana M. Crane, Emmanuel Olivier, Laurent Poirot, Roman Galetto, Penelope Kosinski, Collin Hill, Charles Kung, Xabi Agirre, Israel Orman, Laura Cerrato, Omaira Alberquilla, Fatima Rodriguez-Fornes, Noemi Fusaki, Felix Garcia-Sanchez, Tabita M. Maia, Maria L. Ribeiro, Julian Sevilla, Felipe Prosper, Shengfang Jin, Joanne Mountford, Guillermo Guenechea, Agnes Gouble, Juan A. Bueren, Brian R. Davis, Jose C. Segovia
Published 2015-12-01

Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes

by Julián Sevilla, Susana Navarro, Paula Rio, Rebeca Sánchez-Domínguez, Josune Zubicaray, Eva Gálvez, Eva Merino, Elena Sebastián, Carmen Azqueta, José A. Casado, José C. Segovia, Omaira Alberquilla, Massimo Bogliolo, Francisco J. Román-Rodríguez, Yari Giménez, Lise Larcher, Rocío Salgado, Roser M. Pujol, Raquel Hladun, Ana Castillo, Jean Soulier, Sergi Querol, Jesús Fernández, Jonathan Schwartz, Nagore García de Andoín, Ricardo López, Albert Catalá, Jordi Surralles, Cristina Díaz-de-Heredia, Juan A. Bueren
Published 2021-09-01