The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

by Alexandra Lucaciu, Robert Brunkhorst, Josef M. Pfeilschifter, Waltraud Pfeilschifter, Julien Subburayalu
Published 2020-06-01

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells

by Anja Schwiebs, Dominique Thomas, Burkhard Kleuser, Josef M. Pfeilschifter, Heinfried H. Radeke
Published 2017-01-01

Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.

by Kathrin Pfarr, Corina Danciu, Olga Arlt, Christina Neske, Cristina Dehelean, Josef M Pfeilschifter, Heinfried H Radeke
Published 2015-01-01

Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4

by Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke
Published 2021-08-01

Activation-induced cell death of dendritic cells is dependent on sphingosine kinase 1

by Anja eSchwiebs, Olga eFriesen, Elisabeth eKatzy, Nerea eFerreirós Bouzas, Josef M Pfeilschifter, Heinfried H. Radeke
Published 2016-04-01

Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis.

by Claudia A Nold-Petry, Thomas Lehrnbecher, Andrea Jarisch, Dirk Schwabe, Josef M Pfeilschifter, Heiko Muhl, Marcel F Nold, Marcel F Nold
Published 2010-01-01

Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs

by Caroline Dreis, Florian M. Ottenlinger, Mateusz Putyrski, Andreas Ernst, Andreas Ernst, Meik Huhn, Katrin G. Schmidt, Josef M. Pfeilschifter, Heinfried H. Radeke
Published 2019-07-01

Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study

by Katrin G. Schmidt, Martina Herrero San Juan, Sandra Trautmann, Lucija Berninger, Anja Schwiebs, Florian M. Ottenlinger, Dominique Thomas, Frank Zaucke, Josef M. Pfeilschifter, Heinfried H. Radeke
Published 2017-09-01

Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease

by Meik Huhn, Martina Herrero San Juan, Balint Melcher, Caroline Dreis, Katrin G. Schmidt, Anja Schwiebs, Janet Collins, Josef M. Pfeilschifter, Michael Vieth, Jürgen Stein, Heinfried H. Radeke
Published 2020-05-01

Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice.

by Selina Christen, Ken Coppieters, Kerstin Rose, Martin Holdener, Monika Bayer, Josef M Pfeilschifter, Edith Hintermann, Matthias G von Herrath, Michel Aurrand-Lions, Beat A Imhof, Urs Christen
Published 2013-01-01