Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.

by Matthew S Barnabei, Joseph M Metzger
Published 2012-01-01

Combinatorial effects of double cardiomyopathy mutant alleles in rodent myocytes: a predictive cellular model of myofilament dysregulation in disease.

by Jennifer Davis, Joseph M Metzger
Published 2010-02-01

Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling.

by Michelle L Asp, Joshua J Martindale, Joseph M Metzger
Published 2013-01-01

Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers

by Evelyne M. Houang, Yuk Y. Sham, Frank S. Bates, Joseph M. Metzger
Published 2018-10-01

Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency.

by Frazer I Heinis, Kristin B Andersson, Geir Christensen, Joseph M Metzger
Published 2013-01-01

Dysregulation of Calcium Handling in Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy: Mechanisms and Experimental Therapeutic Strategies

by Michelle L. Law, Houda Cohen, Ashley A. Martin, Addeli Bez Batti Angulski, Joseph M. Metzger
Published 2020-02-01

Early Detection of Myocardial Bioenergetic Deficits: A 9.4 Tesla Complete Non Invasive 31P MR Spectroscopy Study in Mice with Muscular Dystrophy.

by Weina Cui, Albert Jang, Pengyuan Zhang, Brian Thompson, DeWayne Townsend, Joseph M Metzger, Jianyi Zhang
Published 2015-01-01

Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy.

by Matthew Wheelwright, Zaw Win, Jennifer L Mikkila, Kamilah Y Amen, Patrick W Alford, Joseph M Metzger
Published 2018-01-01

Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo

by Evelyne M Houang, Karen J Haman, Antonio Filareto, Rita C Perlingeiro, Frank S Bates, Dawn A Lowe, Joseph M Metzger
Published 2015-01-01

Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure.

by Nathan J Palpant, Michael L Szatkowski, Wang Wang, DeWayne Townsend, Fikru B Bedada, Lauren G Koch, Steven L Britton, Joseph M Metzger
Published 2009-07-01

Acquisition of a Quantitative, Stoichiometrically Conserved Ratiometric Marker of Maturation Status in Stem Cell-Derived Cardiac Myocytes

by Fikru B. Bedada, Sunny S-K. Chan, Stefania K. Metzger, Liying Zhang, Jianyi Zhang, Daniel J. Garry, Timothy J. Kamp, Michael Kyba, Joseph M. Metzger
Published 2014-10-01

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice

by Kurt W. Prins, MD, PhD, Michelle L. Asp, PhD, Huiliang Zhang, PhD, Wang Wang, MD, PhD, Joseph M. Metzger, PhD
Published 2016-04-01

Social stress is lethal in the mdx model of Duchenne muscular dystrophy

by Maria Razzoli, Angus Lindsay, Michelle L. Law, Christopher M. Chamberlain, William M. Southern, Madeleine Berg, John Osborn, William C. Engeland, Joseph M. Metzger, James M. Ervasti, Alessandro Bartolomucci
Published 2020-05-01

Intracoronary Poloxamer 188 Prevents Reperfusion Injury in a Porcine Model of ST-Segment Elevation Myocardial Infarction

by Jason A. Bartos, MD, PhD, Timothy R. Matsuura, BA, Adamantios Tsangaris, MD, Matthew Olson, MD, Scott H. McKnite, BS, Jennifer N. Rees, PhD, Karen Haman, PhD, Kadambari Chandra Shekar, MS, Matthias L. Riess, MD, PhD, Frank S. Bates, ScD, Joseph M. Metzger, PhD, Demetris Yannopoulos, MD
Published 2016-06-01