Liver-Targeted AAV8 Gene Therapy Ameliorates Skeletal and Cardiovascular Pathology in a Mucopolysaccharidosis IVA Murine Model

by Kazuki Sawamoto, Subha Karumuthil-Melethil, Shaukat Khan, Molly Stapleton, Joseph T. Bruder, Olivier Danos, Shunji Tomatsu
Published 2020-09-01

Gene therapy using an ortholog of human fragile X mental retardation protein partially rescues behavioral abnormalities and EEG activity

by Alexander W.M. Hooper, Hayes Wong, Yosuke Niibori, Rozita Abdoli, Subha Karumuthil-Melethil, Chunping Qiao, Olivier Danos, Joseph T. Bruder, David R. Hampson
Published 2021-09-01

Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

by Joseph T. Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B. Patterson, Maureen E. Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C. Richter King, Thomas L. Richie, Denise L. Doolan
Published 2012-01-01

Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses.

by Joseph T. Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B. Patterson, Maureen E. Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C. Richter King, Thomas L. Richie, Denise L. Doolan
Published 2012-01-01

Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses.

by Joseph T Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B Patterson, Maureen E Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C Richter King, Thomas L Richie, Denise L Doolan
Published 2012-01-01

Sexually dimorphic patterns in electroencephalography power spectrum and autism-related behaviors in a rat model of fragile X syndrome

by Hayes Wong, Alexander W.M. Hooper, Yosuke Niibori, Shiron J. Lee, Luca A. Hategan, Liang Zhang, Subha Karumuthil-Melethil, Sally M. Till, Peter C. Kind, Olivier Danos, Joseph T. Bruder, David R. Hampson
Published 2020-12-01

Profiling the Targets of Protective CD8+ T Cell Responses to Infection

by Joseph T. Bruder, Ping Chen, Greg Ekberg, Emily C. Smith, Christopher A. Lazarski, Bennett A. Myers, Jessica Bolton, Martha Sedegah, Eileen Villasante, Thomas L. Richie, C. Richter King, Joao C. Aguiar, Denise L. Doolan, Douglas E. Brough
Published 2017-12-01

A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates.

by Neal N Padte, Mar Boente-Carrera, Chasity D Andrews, Jenny McManus, Brooke F Grasperge, Agegnehu Gettie, Jordana G Coelho-dos-Reis, Xiangming Li, Douglass Wu, Joseph T Bruder, Martha Sedegah, Noelle Patterson, Thomas L Richie, Chi-Huey Wong, David D Ho, Sandhya Vasan, Moriya Tsuji
Published 2013-01-01

Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies.

by George Jiang, Meng Shi, Solomon Conteh, Nancy Richie, Glenna Banania, Harini Geneshan, Anais Valencia, Priti Singh, Joao Aguiar, Keith Limbach, Kurt I Kamrud, Jonathan Rayner, Jonathan Smith, Joseph T Bruder, C Richter King, Takafumi Tsuboi, Satoru Takeo, Yaeta Endo, Denise L Doolan, Thomas L Richie, Walter R Weiss
Published 2009-08-01

New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model

by Keith Limbach, Maureen Stefaniak, Ping Chen, Noelle B. Patterson, Grant Liao, Shaojie Weng, Svetlana Krepkiy, Greg Ekberg, Holly Torano, Damodar Ettyreddy, Kalpana Gowda, Sharvari Sonawane, Arnel Belmonte, Esteban Abot, Martha Sedegah, Michael R. Hollingdale, Ann Moormann, John Vulule, Eileen Villasante, Thomas L. Richie, Douglas E. Brough, Joseph T. Bruder
Published 2017-07-01

Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults.

by Martha Sedegah, Cindy Tamminga, Shannon McGrath, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Nalini Manohar, Nancy O Richie, Chloe Wood, Carole A Long, David Regis, Francis T Williams, Meng Shi, Ilin Chuang, Michele Spring, Judith E Epstein, Jose Mendoza-Silveiras, Keith Limbach, Noelle B Patterson, Joseph T Bruder, Denise L Doolan, C Richter King, Lorraine Soisson, Carter Diggs, Daniel Carucci, Sheetij Dutta, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Published 2011-01-01

Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component.

by Cindy Tamminga, Martha Sedegah, David Regis, Ilin Chuang, Judith E Epstein, Michele Spring, Jose Mendoza-Silveiras, Shannon McGrath, Santina Maiolatesi, Sharina Reyes, Victoria Steinbeiss, Charlotte Fedders, Kathryn Smith, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Jittawadee Murphy, Jack Komisar, Jackie Williams, Meng Shi, Donald Brambilla, Nalini Manohar, Nancy O Richie, Chloe Wood, Keith Limbach, Noelle B Patterson, Joseph T Bruder, Denise L Doolan, C Richter King, Carter Diggs, Lorraine Soisson, Daniel Carucci, Gail Levine, Sheetij Dutta, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Published 2011-01-01

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity.

by Ilin Chuang, Martha Sedegah, Susan Cicatelli, Michele Spring, Mark Polhemus, Cindy Tamminga, Noelle Patterson, Melanie Guerrero, Jason W Bennett, Shannon McGrath, Harini Ganeshan, Maria Belmonte, Fouzia Farooq, Esteban Abot, Jo Glenna Banania, Jun Huang, Rhonda Newcomer, Lisa Rein, Dianne Litilit, Nancy O Richie, Chloe Wood, Jittawadee Murphy, Robert Sauerwein, Cornelus C Hermsen, Andrea J McCoy, Edwin Kamau, James Cummings, Jack Komisar, Awalludin Sutamihardja, Meng Shi, Judith E Epstein, Santina Maiolatesi, Donna Tosh, Keith Limbach, Evelina Angov, Elke Bergmann-Leitner, Joseph T Bruder, Denise L Doolan, C Richter King, Daniel Carucci, Sheetij Dutta, Lorraine Soisson, Carter Diggs, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Published 2013-01-01