High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis

by Jianxun Han, Juan Carlos Zúñiga-Pflücker, Juan Carlos Zúñiga-Pflücker
Published 2021-03-01

Thymic Engraftment by in vitro-Derived Progenitor T Cells in Young and Aged Mice

by Jastaranpreet Singh, Mahmood Mohtashami, Graham Anderson, Juan Carlos Zúñiga-Pflücker, Juan Carlos Zúñiga-Pflücker
Published 2020-08-01

Control of HIV Infection In Vivo Using Gene Therapy with a Secreted Entry Inhibitor

by Alexander Falkenhagen, Jastaranpreet Singh, Sabah Asad, Danila Leontyev, Stanley Read, Juan Carlos Zúñiga-Pflücker, Sadhna Joshi
Published 2017-12-01

Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence

by Nafees Rahman, Patrick M. Brauer, Lilian Ho, Tatiana Usenko, Mukul Tewary, Juan Carlos Zúñiga-Pflücker, Peter W. Zandstra
Published 2017-05-01

Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis

by Yang Li, Patrick M. Brauer, Jastaranpreet Singh, Sintia Xhiku, Kogulan Yoganathan, Juan Carlos Zúñiga-Pflücker, Michele K. Anderson
Published 2017-09-01

T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures

by Marion Kennedy, Geneve Awong, Christopher M. Sturgeon, Andrea Ditadi, Ross LaMotte-Mohs, Juan Carlos Zúñiga-Pflücker, Gordon Keller
Published 2012-12-01

Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency.

by Alexandra Berger, Catherine Frelin, Divya K Shah, Patricia Benveniste, Robert Herrington, Norma P Gerard, Juan-Carlos Zúñiga-Pflücker, Norman N Iscove, Christopher J Paige
Published 2013-01-01

HEB is required for the specification of fetal IL-17-producing γδ T cells

by Tracy S. H. In, Ashton Trotman-Grant, Shawn Fahl, Edward L. Y. Chen, Payam Zarin, Amanda J. Moore, David L. Wiest, Juan Carlos Zúñiga-Pflücker, Michele K. Anderson
Published 2017-12-01

DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system

by Ashton C. Trotman-Grant, Mahmood Mohtashami, Joshua De Sousa Casal, Elisa C. Martinez, Dylan Lee, Sintia Teichman, Patrick M. Brauer, Jianxun Han, Michele K. Anderson, Juan Carlos Zúñiga-Pflücker
Published 2021-08-01

FOXN1GFP/w Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1+ Thymic Epithelial Progenitors

by Chew-Li Soh, Antonietta Giudice, Robert A. Jenny, David A. Elliott, Tanya Hatzistavrou, Suzanne J. Micallef, Korosh Kianizad, Natalie Seach, Juan Carlos Zúñiga-Pflücker, Ann P. Chidgey, Alan Trounson, Susan K. Nilsson, David N. Haylock, Richard L. Boyd, Andrew G. Elefanty, Edouard G. Stanley
Published 2014-06-01