Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages.

by Alexandra K Marr, Julia L MacIsaac, Ruiwei Jiang, Adriana M Airo, Michael S Kobor, W Robert McMaster
Published 2014-10-01

Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

by Sumaiya A. Islam, Sarah J. Goodman, Julia L. MacIsaac, Jelena Obradović, Ronald G. Barr, W. Thomas Boyce, Michael S. Kobor
Published 2019-01-01

DNA methylation differences associated with social anxiety disorder and early life adversity

by Ariane Wiegand, Benjamin Kreifelts, Matthias H. J. Munk, Nadja Geiselhart, Katia E. Ramadori, Julia L. MacIsaac, Andreas J. Fallgatter, Michael S. Kobor, Vanessa Nieratschker
Published 2021-02-01

DNA methylation as a predictor of fetal alcohol spectrum disorder

by Alexandre A. Lussier, Alexander M. Morin, Julia L. MacIsaac, Jenny Salmon, Joanne Weinberg, James N. Reynolds, Paul Pavlidis, Albert E. Chudley, Michael S. Kobor
Published 2018-01-01

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

by Lucas T. Husquin, Maxime Rotival, Maud Fagny, Hélène Quach, Nora Zidane, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Hugues Aschard, Etienne Patin, Lluis Quintana-Murci
Published 2018-12-01

DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment

by Christof Brückmann, Sumaiya A. Islam, Julia L. MacIsaac, Alexander M. Morin, Kathrin N. Karle, Adriana Di Santo, Richard Wüst, Immanuel Lang, Anil Batra, Michael S. Kobor, Vanessa Nieratschker
Published 2017-07-01

Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

by Lisa M. McEwen, Alexander M. Morin, Rachel D. Edgar, Julia L. MacIsaac, Meaghan J. Jones, William H. Dow, Luis Rosero-Bixby, Michael S. Kobor, David H. Rehkopf
Published 2017-04-01

Analysis of two birth tissues provides new insights into the epigenetic landscape of neonates born preterm

by Yonghui Wu, Xinyi Lin, Ives Yubin Lim, Li Chen, Ai Ling Teh, Julia L. MacIsaac, Kok Hian Tan, Michael S. Kobor, Yap Seng Chong, Peter D. Gluckman, Neerja Karnani
Published 2019-02-01

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

by Rachel L. Clifford, Nick Fishbane, Jamie Patel, Julia L. MacIsaac, Lisa M. McEwen, Andrew J. Fisher, Corry-Anke Brandsma, Parameswaran Nair, Michael S. Kobor, Tillie-Louise Hackett, Alan J. Knox
Published 2018-03-01

Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs

by Alexander M. Morin, Evan Gatev, Lisa M. McEwen, Julia L. MacIsaac, David T. S. Lin, Nastassja Koen, Darina Czamara, Katri Räikkönen, Heather J. Zar, Karestan Koenen, Dan J. Stein, Michael S. Kobor, Meaghan J. Jones
Published 2017-07-01

Maternal psychosocial risk factors and child gestational epigenetic age in a South African birth cohort study

by Nastassja Koen, Meaghan J. Jones, Raymond T. Nhapi, Marilyn T. Lake, Kirsten A. Donald, Whitney Barnett, Nadia Hoffman, Julia L. MacIsaac, Alexander M. Morin, David T. S. Lin, Michael S. Kobor, Karestan C. Koenen, Heather J. Zar, Dan J. Stein
Published 2021-07-01

Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array

by Lisa M McEwen, Meaghan J Jones, David Tse Shen Lin, Rachel D Edgar, Lucas T Husquin, Julia L MacIsaac, Katia E Ramadori, Alexander M Morin, Christopher F Rider, Chris Carlsten, Lluís Quintana-Murci, Steve Horvath, Michael S Kobor
Published 2018-10-01

Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial.

by Elie Antoun, Negusse T Kitaba, Philip Titcombe, Kathryn V Dalrymple, Emma S Garratt, Sheila J Barton, Robert Murray, Paul T Seed, Joanna D Holbrook, Michael S Kobor, David Ts Lin, Julia L MacIsaac, Graham C Burdge, Sara L White, Lucilla Poston, Keith M Godfrey, Karen A Lillycrop, UPBEAT Consortium
Published 2020-11-01

PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores

by Lawrence M. Chen, Nelson Yao, Elika Garg, Yuecai Zhu, Thao T. T. Nguyen, Irina Pokhvisneva, Shantala A. Hari Dass, Eva Unternaehrer, Hélène Gaudreau, Marie Forest, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Celia M. T. Greenwood, Patricia P. Silveira, Michael J. Meaney, Kieran J. O’Donnell
Published 2018-08-01

Choice of surrogate tissue influences neonatal EWAS findings

by Xinyi Lin, Ai Ling Teh, Li Chen, Ives Yubin Lim, Pei Fang Tan, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Yung Seng Lee, Joanna D. Holbrook, Keith M. Godfrey, Michael J. Meaney, Michael S. Kobor, Yap Seng Chong, Peter D. Gluckman, Neerja Karnani
Published 2017-12-01